| Type | Description |
|---|---|
| Definition | otospiralin |
| Date | Results | Publications |
|---|---|---|
| 2015-09-12 11:31:00 | study indicates a potentially protective role for the variant G alleles of SNPs rs77124181 and rs2291767 in Otos against the development of cisplatin-induced ototoxicity | 25410892 |
| 2010-01-21 00:00:00 | OTOSP spans 1630 nucleotides, has 4 exons & encodes a 567-base cDNA. OTOSP is on chromosome 2 at position q37.3. Beside intronic polymorphisms, a rare variant (Pro7Leu) was found in deafness patients & controls, excluding it as a genetic deafness gene. | 12687421 |
| Type | IDs |
|---|---|
| Synonymous | OTOSP |
| Gene |
UniProtKB-ID:
OTOSP_HUMAN
UniprotKB:
Q8NHW6
UniParc:
UPI00000704B2
EMBL:
BC105087,
BC105085,
AC013469,
AY062256
Ensembl:
ENSG00000178602
KO:
hsa:150677
|
| Nucleutide sequences |
EMBL-CDS:
AAI05088.1,
AAY14739.1,
AAI05086.1,
AAL47489.1
Ensembl_TRS:
ENST00000391989,
ENST00000319460
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000322486,
ENSP00000375849
RefSeq:
XP_016858898.1,
XP_016858899.1,
NP_683764.1
|
| Others |
UniRef100:
UniRef100_Q8NHW6
UniRef90:
UniRef90_Q8NHW6
UniRef50:
UniRef50_Q8NHW6
UniGene:
Hs.148586
CCDS:
CCDS2533.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 25410892 |
Genetic variation in Otos is associated with cisplatin-induced ototoxicity. Pharmacogenomics Timothy F Spracklen , Heather Whitehorn , Anna Alvera Vorster , Lebogang Ramma , Sameera Dalvie , Rajkumar S Ramesar |
2014-09-01 |
OTOS
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 15815621 |
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature Ladeana W Hillier , Tina A Graves , Robert S Fulton , Lucinda A Fulton , Kymberlie H Pepin , Patrick Minx , Caryn Wagner-McPherson , Dan Layman , Kristine Wylie , Mandeep Sekhon , Michael C Becker , Ginger A Fewell , Kimberly D Delehaunty , Tracie L Miner , William E Nash , Colin Kremitzki , Lachlan Oddy , Hui Du , Hui Sun , Holland Bradshaw-Cordum , Johar Ali , Jason Carter , Matt Cordes , Anthony Harris , Amber Isak , Andrew van Brunt , Christine Nguyen , Feiyu Du , Laura Courtney , Joelle Kalicki , Philip Ozersky , Scott Abbott , Jon Armstrong , Edward A Belter , Lauren Caruso , Maria Cedroni , Marc Cotton , Teresa Davidson , Anu Desai , Glendoria Elliott , Thomas Erb , Catrina Fronick , Tony Gaige , William Haakenson , Krista Haglund , Andrea Holmes , Richard Harkins , Kyung Kim , Scott S Kruchowski , Cynthia Madsen Strong , Neenu Grewal , Ernest Goyea , Shunfang Hou , Andrew Levy , Scott Martinka , Kelly Mead , Michael D McLellan , Rick Meyer , Jennifer Randall-Maher , Chad Tomlinson , Sara Dauphin-Kohlberg , Amy Kozlowicz-Reilly , Neha Shah , Sharhonda Swearengen-Shahid , Jacqueline Snider , Joseph T Strong , Johanna Thompson , Martin Yoakum , Shawn Leonard , Charlene Pearman , Lee Trani , Maxim Radionenko , Jason E Waligorski , Chunyan Wang , Susan M Rock , Aye-Mon Tin-Wollam , Rachel Maupin , Phil Latreille , Michael C Wendl , Shiaw-Pyng Yang , Craig Pohl , John W Wallis , John Spieth , Tamberlyn A Bieri , Nicolas Berkowicz , Joanne O Nelson , John Osborne , Li Ding , Rekha Meyer , Aniko Sabo , Yoram Shotland , Prashant Sinha , Patricia E Wohldmann , Lisa L Cook , Matthew T Hickenbotham , James Eldred , Donald Williams , Thomas A Jones , Xinwei She , Francesca D Ciccarelli , Elisa Izaurralde , James Taylor , Jeremy Schmutz , Richard M Myers , David R Cox , Xiaoqiu Huang , John D McPherson , Elaine R Mardis , Sandra W Clifton , Wesley C Warren , Asif T Chinwalla , Sean R Eddy , Marco A Marra , Ivan Ovcharenko , Terrence S Furey , Webb Miller , Evan E Eichler , Peer Bork , Mikita Suyama , David Torrents , Robert H Waterston , Richard K Wilson |
2005-04-07 |
NEMP2,
SP9,
GKN3P,
CLDN24,
LOC100133128,
ARHGEF33,
LIMS4,
DUX4L9,
ACTR1B,
USP17L23,
CEBPZ,
TXNDC9,
STAM2,
SPEG,
NMUR1,
UBE2E3,
STK25,
SEMA4F,
CCT7,
CCT4,
CENPA,
CDC42EP3,
MXD4,
STAMBP,
TBR1,
MAP3K2,
MTHFD2,
PROKR1,
PPBPP2,
ADCY3,
GPR75,
SNRNP27,
RABL2A,
CHN1,
GPR45,
CFAP36,
CHRND,
CHRNG,
GALNT13,
DIRC1,
MOGAT1,
ARAP2,
ADD1,
ADD2,
CNGA3,
COL3A1,
COL4A3,
COL5A2,
TMEM150A,
NUP35,
MITD1,
NEU4,
UBTFL3,
BBS5,
ICA1L,
REG3G,
RFTN2,
ACVR1C,
OSR1,
UBR3,
KCTD18,
CPO,
PQLC3,
TMEM155,
PACRGL,
COX7A2P2,
MYO3B,
UBE2F,
CRYGB,
CRYGD,
DUSP19,
CTLA4,
CTNNA2,
TEKT4,
C2orf15,
OTOS,
FBXO41,
SEPT10,
ADRA2B,
SGO2,
ALS2CR11,
FAM84A,
ASPRV1,
WDSUB1,
UPP2,
GPR155,
NFXL1,
MGAT4D,
PPM1K,
TRMT44,
DBI,
DAW1,
OXER1,
FREM3,
TIGD2,
AGA,
DOK1,
E2F6,
EEF1B2
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 12687421 |
Neurogenetics Mireille Lavigne-Rebillard , Benjamin Delprat , Marie-Odile Surget , Jean-Michel Griffoin , Dominique Weil , Mariona Arbones , Robert Vincent , Christian P Hamel |
2003-04-01 |
OTOS
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 11880501 |
J. Neurosci. Benjamin Delprat , Ana Boulanger , Jing Wang , Vicky Beaudoin , Matthieu J Guitton , Stephanie Ventéo , Claude J Dechesne , Rémy Pujol , Mireille Lavigne-Rebillard , Jean-Luc Puel , Christian P Hamel |
2002-03-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员