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15064 Mr1

15064

Mr1

major histocompatibility complex, class I-related

protein-coding

Mus musculus

基因描述

Type Description
Definition major histocompatibility complex, class I-related

研究结论

Date Results Publications
2020-12-19 13:44:00 Brain astrocytes and microglia express functional MR1 molecules that present microbial antigens to mucosal-associated invariant T (MAIT) cells. 33096293
2020-04-04 13:03:00 Study of wild-type (WT) and Mr1-/- mice were treated with antibiotics and then infected with Clostridium difficile (Cd) spores. Mr1-/- mice exhibited resistance to Cd colonization. This colonization resistance was transferred from Mr1-/- to WT mice via fecal microbiota transplantation, suggesting that Mr1-dependent factors influence the microbiota, leading to Clostridium difficile infection susceptibility. 31560732
2018-03-31 11:47:00 Here the authors demonstrate that major histocompatibility complex class I deficiency results in significant dendritic atrophy along with an increase in thin dendritic spines and a reduction in stubby spines in the hippocampus of aged (12 month old) mice. 27229916
2013-12-21 11:26:00 MR1 tetramers allow precise phenotypic characterization of human and mouse mucosal-associated invariant T cells. 24101382
2013-07-06 11:24:00 differential contribution of particular amino acids to the MAIT TCR-MR1 interaction based upon the presence of bacteria 23342002

名称对应

Type IDs
Synonymous H2ls
Gene
UniProtKB-ID: HMR1_MOUSE
UniprotKB: Q8HWB0
UniParc: UPI00000228FC, UPI000008B053
EMBL: U94989, AF068692, AK042119, AF068691, BC026137, AF035672, AF010448
Ensembl: ENSMUSG00000026471
KO: mmu:15064
Nucleutide sequences
EMBL-CDS: AAD01444.1, AAD17568.1, AAD02040.1, AAB81345.1, BAC31174.1, AAH26137.1
Ensembl_TRS: ENSMUST00000027744
Protein sequencees
Ensembl_PRO: ENSMUSP00000027744
RefSeq: NP_001341992.1, NP_001341991.1, NP_032235.1
Others
UniRef100: UniRef100_Q8HWB0
UniRef90: UniRef90_Q8HWB0
UniRef50: UniRef50_Q95460
UniGene: Mm.7580
CCDS: CCDS15383.1

全选

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研究热度

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