| Type | Description |
|---|---|
| Definition | SET and MYND domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:13:00 | Stability of Smyd1 in endothelial cells is controlled by PML-dependent SUMOylation upon cytokine stimulation. | 33241844 |
| 2020-10-24 14:05:00 | Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues. | 31097748 |
| 2019-11-23 12:48:00 | This novel mutation (c.814T>C/p.F272L) may be the first identified disease-causing mutation of SMYD1 in Hypertrophic cardiomyopathy (HCM) patients worldwide. | 30205637 |
| 2018-12-29 11:28:00 | We present genetic and statistical evidence that the R320Q substitution in SMYD1 underlies an inherited form of the AnWj-negative blood group phenotype. The mechanism by which the mutation leads to this phenotype remains to be determined. | 29956848 |
| 2016-07-30 10:47:00 | SMYD1 serves as an Serum Response Factor-interacting protein, enhances Serum Response Factor DNA binding activity, and is required for endothelial cell migration and tube formation to regulate angiogenesis. | 26799706 |
| Type | IDs |
|---|---|
| Synonymous | BOP, KMT3D, ZMYND18, ZMYND22 |
| Gene |
UniProtKB-ID:
SMYD1_HUMAN,
Q5HYE8_HUMAN,
E9PHG3_HUMAN
UniprotKB:
Q8NB12,
Q5HYE8,
E9PHG3
UniParc:
UPI000198C5D4,
UPI000006EB68,
UPI00004C414E
EMBL:
AL832035,
AC092836,
AK091724,
BC126191,
BX647878
Ensembl:
ENSG00000115593
KO:
hsa:150572
|
| Nucleutide sequences |
EMBL-CDS:
CAI46139.1,
BAC03732.1,
AAI26192.1,
CAI46077.1
Ensembl_TRS:
ENST00000419482,
ENST00000444564
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000393453,
ENSP00000407888
RefSeq:
NP_001317293.1,
NP_938015.1
|
| Others |
UniRef100:
UniRef100_Q8NB12,
UniRef100_E9PHG3,
UniRef100_Q5HYE8
UniRef90:
UniRef90_E9PHG3,
UniRef90_Q8NB12
UniRef50:
UniRef50_Q8NB12,
UniRef50_Q2MJQ9
UniGene:
Hs.516176
CCDS:
CCDS33240.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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