| Type | Description |
|---|---|
| Definition | histocompatibility 2, T region locus 23 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:10:00 | The murine CD94/NKG2 ligand, Qa-1(b), is a high-affinity, functional ligand for the CD8alphaalpha homodimer. | 31992596 |
| 2020-07-18 10:53:00 | Study using mouse model that harbors a point mutation in the class Ib MHC molecule Qa-1, which disrupts Qa-1 binding to the T cell receptor-CD8 complex and impairs the CD8 Treg response, revealed that Qa-1 mutant mice developed robust donor-specific antibody responses and accelerated heart graft rejection. Findings underscore the critical contribution of Qa-1-dependent regulatory pathway to graft survival. | 32111690 |
| 2020-06-27 10:32:00 | Authors demonstrate that the MHC class Ib molecule Qa-1 (encoded by H2-T23) restricts a large, and critical, portion of this population. These findings reveal a potential adaptation of the host immune response to compensate for viral evasion of classical T cell immunity. | 30970256 |
| 2019-04-13 12:23:00 | Reduced expression of Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer. | 28740236 |
| 2014-09-20 13:02:00 | In this study of C57BL mice, both H2-T23b and H2-T11b histocompatibility antigens are functional genes. | 24958902 |
| Type | IDs |
|---|---|
| Synonymous | 37b, 37c, H-2T23, H2-K1, H2-Qa1, Qa-1, Qa-1(b), Qa1, Qed-1, T18c, T18c(37), T23b, T23d |
| Gene |
UniProtKB-ID:
HA15_MOUSE,
Q3V014_MOUSE,
Q31153_MOUSE
UniprotKB:
P06339,
Q3V014,
Q31153
UniParc:
UPI00000894FE,
UPI0000028A7E
EMBL:
Y00629,
M11284,
BC005648,
L00606,
AF041855,
AK133502
Ensembl:
ENSMUSG00000067212
KO:
mmu:15040
|
| Nucleutide sequences |
EMBL-CDS:
AAA39693.1,
CAA68665.1,
BAE21691.1,
AAH05648.1,
AAA16900.1,
AAD53968.1
Ensembl_TRS:
ENSMUST00000102678
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099739
RefSeq:
NP_034528.1
|
| Others |
UniRef100:
UniRef100_P06339,
UniRef100_Q31153
UniRef90:
UniRef90_P06339,
UniRef90_Q31153
UniRef50:
UniRef50_P06339
UniGene:
Mm.439648,
Mm.441651
CCDS:
CCDS28715.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员