| Type | Description |
|---|---|
| Definition | chymotrypsinogen B1 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-22 11:35:00 | An inversion in the CTRB1-CTRB2 locus modifies risk for Alcoholic and Non-alcoholic Chronic Pancreatitis indicating that common pathomechanisms are involved in these inflammatory disorders. | 28754779 |
| 2017-07-29 10:59:00 | Two protective, low-frequency, non-synonymous variants were significantly associated with a decrease in age-related macular degeneration (AMD)risk: A307V in PELI3 and N1050Y in CFH .We also identified a strong protective signal for a common variant (rs8056814) near CTRB1 associated with a decrease in AMD risk (logistic regression: OR = 0.71, P = 1.8 x 10-07). | 28011711 |
| 2009-12-02 21:41:00 | Observational study of gene-disease association. (HuGE Navigator) | 19844255 |
| Type | IDs |
|---|---|
| Synonymous | CTRB |
| Gene |
UniProtKB-ID:
CTRB1_HUMAN
UniprotKB:
P17538
UniParc:
UPI000013E843
EMBL:
AC009078,
BT007356,
BC005385,
M24400
Ensembl:
ENSG00000168925
KO:
hsa:1504
|
| Nucleutide sequences |
EMBL-CDS:
AAA52128.1,
AAH05385.1,
AAP36020.1
Ensembl_TRS:
ENST00000361017
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354294
RefSeq:
NP_001316119.1,
NP_001897.4
|
| Others |
UniRef100:
UniRef100_P17538
UniRef90:
UniRef90_P17538
UniRef50:
UniRef50_P07338
UniGene:
Hs.610926
CCDS:
CCDS32490.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33036922 |
Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis. Pancreatology Katharina Seltsam , Carola Pentner , Franziska Weigl , Stella Sutedjo , Constantin Zimmer , Sebastian Beer , Peter Bugert , Maren Ewers , Claudia Ruffert , Patrick Michl , Helmut Laumen , Heiko Witt , Jonas Rosendahl |
2020-12-01 | - |
| 28754779 |
locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut Jonas Rosendahl , Holger Kirsten , Eszter Hegyi , Peter Kovacs , Frank Ulrich Weiss , Helmut Laumen , Peter Lichtner , Claudia Ruffert , Jian-Min Chen , Emmanuelle Masson , Sebastian Beer , Constantin Zimmer , Katharina Seltsam , Hana Algül , Florence Bühler , Marco J Bruno , Peter Bugert , Ralph Burkhardt , Giulia Martina Cavestro , Halina Cichoz-Lach , Antoni Farré , Josef Frank , Giovanni Gambaro , Sebastian Gimpfl , Harald Grallert , Heidi Griesmann , Robert Grützmann , Claus Hellerbrand , Péter Hegyi , Marcus Hollenbach , Sevastitia Iordache , Grazyna Jurkowska , Volker Keim , Falk Kiefer , Sebastian Krug , Olfert Landt , Milena Di Leo , Markus M Lerch , Philippe Lévy , Markus Löffler , Matthias Löhr , Maren Ludwig , Milan Macek , Nuria Malats , Ewa Malecka-Panas , Giovanni Malerba , Karl Mann , Julia Mayerle , Sonja Mohr , Rene H M Te Morsche , Marie Motyka , Sebastian Mueller , Thomas Müller , Markus M Nöthen , Sergio Pedrazzoli , Stephen P Pereira , Annette Peters , Roland Pfützer , Francisco X Real , Vinciane Rebours , Monika Ridinger , Marcella Rietschel , Eva Rösmann , Adrian Saftoiu , Alexander Schneider , Hans-Ulrich Schulz , Nicole Soranzo , Michael Soyka , Peter Simon , James Skipworth , Felix Stickel , Konstantin Strauch , Michael Stumvoll , Pier Alberto Testoni , Anke Tönjes , Lena Werner , Jens Werner , Norbert Wodarz , Martin Ziegler , Atsushi Masamune , Joachim Mössner , Claude Férec , Patrick Michl , Joost P H Drenth , Heiko Witt , Markus Scholz , Miklós Sahin-Tóth , all members of the PanEuropean Working group on ACP |
2018-10-01 | - |
| 28951524 |
Gut Xin-Ying Tang , Wen-Bin Zou , Emmanuelle Masson , Liang-Hao Hu , Claude Ferec , Jian-Min Chen , Zhao-Shen Li , Zhuan Liao |
2018-07-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 28011711 |
Hum. Mol. Genet. Yi Yu , Erin K Wagner , Eric H Souied , Sanna Seitsonen , Ilkka J Immonen , Paavo Häppölä , Soumya Raychaudhuri , Mark J Daly , Johanna M Seddon |
2016-12-01 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25086665 |
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. Nat Genet Brian M Wolpin , Cosmeri Rizzato , Peter Kraft , Charles Kooperberg , Gloria M Petersen , Zhaoming Wang , Alan A Arslan , Laura Beane-Freeman , Paige M Bracci , Julie Buring , Federico Canzian , Eric J Duell , Steven Gallinger , Graham G Giles , Gary E Goodman , Phyllis J Goodman , Eric J Jacobs , Aruna Kamineni , Alison P Klein , Laurence N Kolonel , Matthew H Kulke , Donghui Li , Núria Malats , Sara H Olson , Harvey A Risch , Howard D Sesso , Kala Visvanathan , Emily White , Wei Zheng , Christian C Abnet , Demetrius Albanes , Gabriella Andreotti , Melissa A Austin , Richard Barfield , Daniela Basso , Sonja I Berndt , Marie-Christine Boutron-Ruault , Michelle Brotzman , Markus W Büchler , H Bas Bueno-de-Mesquita , Peter Bugert , Laurie Burdette , Daniele Campa , Neil E Caporaso , Gabriele Capurso , Charles Chung , Michelle Cotterchio , Eithne Costello , Joanne Elena , Niccola Funel , J Michael Gaziano , Nathalia A Giese , Edward L Giovannucci , Michael Goggins , Megan J Gorman , Myron Gross , Christopher A Haiman , Manal Hassan , Kathy J Helzlsouer , Brian E Henderson , Elizabeth A Holly , Nan Hu , David J Hunter , Federico Innocenti , Mazda Jenab , Rudolf Kaaks , Timothy J Key , Kay-Tee Khaw , Eric A Klein , Manolis Kogevinas , Vittorio Krogh , Juozas Kupcinskas , Robert C Kurtz , Andrea LaCroix , Maria T Landi , Stefano Landi , Loic Le Marchand , Andrea Mambrini , Satu Mannisto , Roger L Milne , Yusuke Nakamura , Ann L Oberg , Kouros Owzar , Alpa V Patel , Petra H M Peeters , Ulrike Peters , Raffaele Pezzilli , Ada Piepoli , Miquel Porta , Francisco X Real , Elio Riboli , Nathaniel Rothman , Aldo Scarpa , Xiao-Ou Shu , Debra T Silverman , Pavel Soucek , Malin Sund , Renata Talar-Wojnarowska , Philip R Taylor , George E Theodoropoulos , Mark Thornquist , Anne Tjønneland , Geoffrey S Tobias , Dimitrios Trichopoulos , Pavel Vodicka , Jean Wactawski-Wende , Nicolas Wentzensen , Chen Wu , Herbert Yu , Kai Yu , Anne Zeleniuch-Jacquotte , Robert Hoover , Patricia Hartge , Charles Fuchs , Stephen J Chanock , Rachael S Stolzenberg-Solomon , Laufey T Amundadottir |
2014-09-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 19844255 |
Eur. J. Hum. Genet. Zari Dastani , Päivi Pajukanta , Michel Marcil , Nicholas Rudzicz , Isabelle Ruel , Swneke D Bailey , Jenny C Lee , Mathieu Lemire , Janet Faith , Jill Platko , John Rioux , Thomas J Hudson , Daniel Gaudet , James C Engert , Jacques Genest |
2010-03-01 |
CLEC3A,
CFDP1,
GABARAPL2,
PKD1L2,
CDYL2,
TMEM170A,
CTRB1,
ZFP1,
ADAMTS18,
LDHD,
MLKL,
MON1B,
ATMIN,
ADAT1,
CHST5,
GCSH,
GLG1,
NUDT7,
KARS,
MAF,
CHST6,
WWOX,
BCO1,
TERF2IP,
RFWD3,
CMC2,
PSMD7,
VAT1L,
FA2H,
WDR59,
GAN,
DYNLRB2,
ZNRF1,
CNTNAP4,
BCAR1
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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