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1503 CTPS1

1503

CTPS1

CTP synthase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition CTP synthase 1

研究结论

Date Results Publications
2017-12-02 10:59:00 CTP synthase forms the cytoophidium in human hepatocellular carcinoma. 29097181
2017-07-15 12:15:00 The filament structures elucidate allosteric mechanisms of assembly and regulation that rely on a conserved conformational equilibrium. The findings may provide a mechanism for increasing human CTP synthase activity in response to metabolic state and challenge the assumption that metabolic filaments are generally storage forms of inactive enzymes. 28459447
2014-09-06 11:44:00 Rods and rings (RR) are protein assemblies composed of CTPS1 and IMPDH2. Glutamine deprivation initiates reversible assembly of mammalian rods and rings. 24477477
2014-07-19 11:40:00 results highlight a key and specific role of CTPS1 in the immune system by its capacity to sustain the proliferation of activated lymphocytes during the immune response 24870241
2010-11-27 10:09:00 analysis of the kinetic properties of hCTPS1 and hCTPS2, and determination that Ser(68) is a major site of CTPS2 regulation by phosphorylation 20739275

名称对应

Type IDs
Synonymous CTPS, GATD5, IMD24
Gene
UniProtKB-ID: PYRG1_HUMAN, B4E1E0_HUMAN
UniprotKB: P17812, B4E1E0
UniParc: UPI0000132D63, UPI00017A8601, UPI00017A7AA9
EMBL: BC009408, AK303797, X52142, CH471059, AK299122, AL391730
Ensembl: ENSG00000171793
KO: hsa:1503
Nucleutide sequences
EMBL-CDS: CAA36386.1, AAH09408.1, BAG61176.1, EAX07192.1, EAX07193.1, BAG64752.1
Ensembl_TRS: ENST00000649124, ENST00000372616, ENST00000650070, ENST00000649215
Protein sequencees
Ensembl_PRO: ENSP00000361699, ENSP00000497744, ENSP00000497602, ENSP00000497698
RefSeq: XP_024309320.1, NP_001896.2, XP_024309329.1, XP_024309322.1, XP_024309321.1, NP_001288166.1
Others
UniRef100: UniRef100_P17812
UniRef90: UniRef90_P17812
UniRef50: UniRef50_P17812
UniGene: Hs.473087
CCDS: CCDS459.1

全选

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