| Type | Description |
|---|---|
| Definition | HscB mitochondrial iron-sulfur cluster cochaperone |
| Date | Results | Publications |
|---|---|---|
| 2019-01-05 11:02:00 | Cytosolic HSC20 is indispensable for cytoplasmic Fe-S assembly and delivery, which is initiated de novo in the cytosol. | 29309586 |
| 2018-12-22 11:28:00 | Nfu is shown to bind to both chaperone proteins with binding affinities similar to those observed for IscU binding to the homologous and Hsc20, while Nfu can also stimulate the ATPase activity of Hduanyu18429 | 29211945 |
| 2017-11-11 13:48:00 | The delivery of assembled Fe-S clusters to recipient proteins is a crucial step in the biogenesis of Fe-S proteins; review focuses on recent insights into the molecular mechanism of amino acid motif recognition and discrimination by the co-chaperone HSC20 and finds co-chaperone HSC20 binds to LYR motifs present in Fe-S recipient proteins or their binding partners. [Review] | 27714045 |
| 2017-07-15 12:05:00 | the crucial role of HSC20 in the assembly of the mitochondrial respiratory chain, is reported. | 28380382 |
| 2013-12-07 11:19:00 | NFS1 binds preferentially to the D-state of ISCU while mtHSP70 binds preferentially to the D-state of ISCU and HSC20 binds preferentially to the S-state of ISCU. | 23940031 |
| Type | IDs |
|---|---|
| Synonymous | DNAJC20, HSC20, JAC1 |
| Gene |
UniProtKB-ID:
HSC20_HUMAN,
B0QYH2_HUMAN,
A0A384NYJ4_HUMAN
UniprotKB:
Q8IWL3,
B0QYH2,
A0A384NYJ4
UniParc:
UPI0000EE5940,
UPI000013C6B6
EMBL:
AL023494,
BC065569,
CR456462,
AY191719,
AL117330,
CH471095,
GQ891495
Ensembl:
ENSG00000100209
KO:
hsa:150274
|
| Nucleutide sequences |
EMBL-CDS:
AAH65569.1,
AAN85282.1,
CAG30348.1,
EAW59760.1,
EAW59758.1,
ADO22357.1
Gene_ORFName:
hCG_40981,
hCG_40981
Ensembl_TRS:
ENST00000216027,
ENST00000398941,
ENST00000420442
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000216027,
ENSP00000381914,
ENSP00000416679
RefSeq:
XP_016884109.1,
XP_005261416.1,
NP_001305243.1,
NP_741999.3,
NP_001350785.1,
NP_001305245.1,
XP_016884108.1,
NP_001305244.1
|
| Others |
UniRef100:
UniRef100_Q8IWL3,
UniRef100_B0QYH2
UniRef90:
UniRef90_B0QYH2,
UniRef90_Q8IWL3
UniRef50:
UniRef50_B0QYH2,
UniRef50_Q8IWL3
UniGene:
Hs.632780
CCDS:
CCDS13845.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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