例如:"NBL1", "4681", "drought"
收藏
150094 SIK1

150094

SIK1

salt inducible kinase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition salt inducible kinase 1

研究结论

Date Results Publications
2021-03-20 13:30:00 Exosomal miR-130b-3p targets SIK1 to inhibit medulloblastoma tumorigenesis. 32483145
2020-11-21 13:13:00 Sodium Channel Nav1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Through its Regulation by the Salt-Inducible Kinase-1. 31819138
2020-08-22 15:31:00 An LKB1-SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation. 31350327
2018-12-22 11:28:00 Data suggest that cAMP/protein kinase A-dependent phosphorylation of SIK1, SIK2, and SIK3 inhibits their catalytic activity by inducing 14-3-3 protein binding. 29211348
2018-06-02 11:58:00 This work reveals a regulatory circuit in which SIK1 suppresses gluconeogenic gene transcription by inducing ubiquitination and degradation of CRTC1. 29408765

名称对应

Type IDs
Synonymous MSK, SIK, SIK-1, SIK1B, SNF1LK
Gene
UniProtKB-ID: SIK1_HUMAN
UniprotKB: P57059
UniParc: UPI0000206F2B
EMBL: BC038504, AB047786, AP001751, AK131076
Ensembl: ENSG00000142178
KO: hsa:102724428, hsa:150094
Nucleutide sequences
EMBL-CDS: BAA95536.1, BAD74070.1, BAC85126.1, AAH38504.1
Ensembl_TRS: ENST00000270162
Protein sequencees
Ensembl_PRO: ENSP00000270162
RefSeq: NP_775490.2, XP_011527776.1
Others
UniRef100: UniRef100_P57059
UniRef90: UniRef90_P57059
UniRef50: UniRef50_P57059
UniGene: Hs.282113, Hs.700423
CCDS: CCDS33575.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员