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15 AANAT

15

AANAT

aralkylamine N-acetyltransferase

protein-coding

Homo sapiens

基因描述

Type Description
Definition aralkylamine N-acetyltransferase

研究结论

Date Results Publications
2020-05-02 10:46:00 Two SNPs of AANAT gene (rs8150 and rs3760138) associated with the risk of systemic lupus erythematosus. 31815152
2017-10-14 11:13:00 Aggregate genetic variation in circadian rhythm and melatonin pathways were significantly associated with the risk of prostate cancer in data combining GAME-ON and PLCO, after Bonferroni correction (ppathway < 0.00625). The two most significant genes were NPAS2 (pgene = 0.0062) and AANAT (pgene = 0.00078); the latter being significant after Bonferroni correction. 28699174
2017-06-24 11:14:00 Data show that arylalkymine N-acetyltransferase (AANAT) levels and melatonin synthesis change after transient receptor potential channel 4 (TRPV4 channel) stimulation in ciliary body epithelial cells. 28368307
2017-05-06 20:52:00 these and related results indicate both a major involvement of the N-end rule pathway in the control of rodent AANATs and substantial differences in the regulation of rodent and human AANATs that stem from differences in their N-terminal sequences. 27339900
2011-11-19 10:59:00 There is dysregulation of the AANAT/ASMT/melatonin --> melatonin receptor axis in cholangiocarcinoma, which inhibited melatonin secretion and subsequently enhanced CCA growth. 21778461

名称对应

Type IDs
Synonymous DSPS, SNAT
Gene
UniProtKB-ID: SNAT_HUMAN, F1T0I5_HUMAN
UniprotKB: Q16613, F1T0I5
UniParc: UPI0000135B1C, UPI000153D76E
EMBL: BC069434, U40391, BC126332, BC092430, AB593119, AC015802, BC126334, U40347, CH471099
Ensembl: ENSG00000129673
KO: hsa:15
Nucleutide sequences
EMBL-CDS: AAC50554.1, AAC50555.1, AAI26333.1, AAI26335.1, AAH92430.1, AAH69434.1, EAW89400.1, BAJ84059.1
Gene_ORFName: hCG_30892
Ensembl_TRS: ENST00000250615, ENST00000392492
Protein sequencees
Ensembl_PRO: ENSP00000376282, ENSP00000250615
RefSeq: NP_001160051.1, NP_001079.1, XP_016879748.1
Others
UniRef100: UniRef100_Q16613
UniRef90: UniRef90_Q16613
UniRef50: UniRef50_Q16613
UniGene: Hs.431417
CCDS: CCDS54169.1, CCDS11745.1

全选

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