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149951 COMMD7

149951

COMMD7

COMM domain containing 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition COMM domain containing 7

研究结论

Date Results Publications
2018-09-15 11:36:00 COMMD7 activates CXCL10 production by regulating NFkappaB and the production of The present study highlighted the role of COMMD7 in the development of HCC, and provides novel options for anticancer drug design. 29532873
2017-12-30 12:34:00 COMMD7 up-regulation is correlated with a novel NF-kappaB positive feedback loop in hepatocellular carcinoma, regulation cell proliferation, cell migration and apoptosis. 27129158
2017-09-02 12:02:00 High COMMD7 expression was specifically detected in pancreatic ductal adenocarcinoma tissues and pancreatic ductal adenocarcinoma cell lines. In addition, COMMD7 overexpression positively correlated with histological differentiation and tumor node metastasis (TNM) stage. 27350032
2017-04-01 11:00:00 The present data suggests a potential role of CXCL10 in the oncogenic function of COMMD7. 28142122
2016-01-23 10:11:00 COMMD7's binding to NEMO does not interfere with the binding to the IKKs, and that the disruption of the IKK complex through the use of the NBP competitor impairs the termination of NF-kappaB activity 26060140

名称对应

Type IDs
Synonymous C20orf92, dJ1085F17.3
Gene
UniProtKB-ID: COMD7_HUMAN
UniprotKB: Q86VX2
UniParc: UPI0000EE4926, UPI000006D145
EMBL: CH471077, BI821799, FO393400, BC000628, AK027893, AK096307, BC047440, BX640505, AL035071, AY542162
Ensembl: ENSG00000149600
KO: hsa:149951
Nucleutide sequences
EMBL-CDS: AAH00628.3, BAB55436.1, EAW76360.1, BAG53254.1, AAH47440.1, AAS22244.1
Ensembl_TRS: ENST00000278980, ENST00000446419
Protein sequencees
Ensembl_PRO: ENSP00000278980, ENSP00000395339
RefSeq: XP_005260357.1, XP_011526906.1, NP_001092809.1, XP_016883176.1, XP_016883175.1, NP_444269.2, XP_005260356.1, XP_016883174.1
Others
UniRef100: UniRef100_Q86VX2
UniRef90: UniRef90_Q86VX2
UniRef50: UniRef50_Q86VX2
UniGene: Hs.408427
CCDS: CCDS42864.1, CCDS46587.1

全选

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研究热度

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