Type | Description |
---|---|
Definition | solute carrier family 39 (zinc transporter), member 7 |
Date | Results | Publications |
---|---|---|
2020-01-18 12:08:00 | we have clarified the functional differences between ZIP7 and ZIP13 and show that their different regulation of cellular zinc homeostasis is critical for dermal development and homeostasis. | 31412620 |
2020-01-04 11:31:00 | Study identified that Zip7 is upregulated by glucose in normal skeletal muscle cells and downregulated in insulin-resistant skeletal muscle. The overexpression of Zip7 in skeletal muscle cells led to the modulation of key genes involved in the insulin signaling axis and glucose metabolism. In vivo mouse model revealed a reduction in Glut4 and Zip7 in the skeletal muscle of mice fed a high-fat diet. | 31266232 |
2019-11-02 10:41:00 | Depletion of zinc transporter Zip7 by RNA interference shows reduction of both PI3K/Akt signalling and a significant reduction of multinucleated myofibres and myotubes development. Moreover, we show that mature myofibres, obtained through stimulation with high concentrations of zinc, accumulate zinc and so we hypothesise their function as zinc reservoirs into the cell | 30206294 |
2017-05-13 16:06:00 | these findings provide evidence for the importance of ZIP7 in maintenance of intestinal epithelial homeostasis through the regulation of ER function in proliferative progenitor cells and maintenance of intestinal stem cells. Therapeutic targeting of ZIP7 could lead to effective treatment of gastrointestinal disorders. | 27736879 |
2014-09-06 11:37:00 | a novel role for Zip7 in glucose metabolism in skeletal muscle | 24265765 |
Type | IDs |
---|---|
Synonymous | AA408174, AI117660, AL024048, H-2Ke4, H2-Ke4, Ke-4, Ke4, Ring5, Zip7 |
Gene |
UniProtKB-ID:
S39A7_MOUSE,
A0A068BIT0_MOUSE
UniprotKB:
Q31125,
A0A068BIT0
UniParc:
UPI00000222FD
EMBL:
M32010,
KJ650218,
AF100956,
AK159968
Ensembl:
ENSMUSG00000024327
KO:
mmu:14977
|
Nucleutide sequences |
EMBL-CDS:
BAE35522.1,
AAC69903.1,
AAA37767.1,
AIC84006.1
Ensembl_TRS:
ENSMUST00000025186,
ENSMUST00000169397
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025186,
ENSMUSP00000130102
RefSeq:
NP_001071177.1,
NP_032228.2
|
Others |
UniRef100:
UniRef100_Q31125
UniRef90:
UniRef90_Q31125
UniRef50:
UniRef50_Q92504
UniGene:
Mm.18556
CCDS:
CCDS37576.1
|
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