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1495 CTNNA1

1495

CTNNA1

catenin alpha 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition catenin alpha 1

研究结论

Date Results Publications
2021-02-20 13:30:00 Molecular mechanism for direct actin force-sensing by alpha-catenin. 32969337
2020-10-24 14:08:00 Salivary Secretory Carcinoma Harboring a Novel ALK Fusion: Expanding the Molecular Characterization of Carcinomas Beyond the ETV6 Gene. 32205481
2020-04-04 11:31:00 The 107-residue intrinsically disordered N-terminal segment of beta-catenin forms a flexible "tongue" that is inserted into alpha-catenin and participates in the assembly of the alpha-catenin*beta-catenin*epithelial cadherin complex. 31591245
2020-01-04 10:10:00 CTNNA1 germline mutation is associated with gastric cancer. 30515673
2019-12-21 10:46:00 MAP3K6 should no longer be considered a gastric cancer (GC) predisposition gene, whereas deleterious CTNNA1 variants are confirmed as an infrequent cause of GC susceptibility. Biallelic MYD88 germline mutations are at most a very rare cause of GC susceptibility. 29330337

名称对应

Type IDs
Synonymous CAP102, MDPT2
Gene
UniProtKB-ID: CTNA1_HUMAN, A0A384MDY0_HUMAN, B4DKT9_HUMAN, G3XAM7_HUMAN, B4DU00_HUMAN
UniprotKB: P35221, A0A384MDY0, B4DKT9, G3XAM7, B4DU00
UniParc: UPI000012862C, UPI00017A7FB9, UPI00006A77DC, UPI000006EF11, UPI0000EE35CE, UPI00017A7504
EMBL: AF102802, AF102799, L23805, AC113340, AK300439, AF102798, L22080, AF102800, AF102803, AF102787, BC031262, AF102794, U03100, AF102788, AF102795, AF102801, AF102796, AC011405, HQ589335, GQ900929, AC010453, AF102793, D14705, KF458015, AF102790, AF102792, AF102789, AF102797, D13866, AC034243, AF102791, CH471062, AK296708, AY884207, BC000385
Ensembl: ENSG00000044115
KO: hsa:1495
Nucleutide sequences
EMBL-CDS: BAA03530.1, AAH00385.1, AAA86430.1, AEF32483.1, AAH31262.1, AAC99459.1, AAW56940.1, BAA02979.1, AAA35502.1, AAA18949.1, EAW62124.1, ADO22446.1, EAW62123.1, BAG59301.1, EAW62122.1, BAG62162.1
Gene_ORFName: hCG_1782385, hCG_1782385
Ensembl_TRS: ENST00000540387, ENST00000302763, ENST00000627109, ENST00000518825
Protein sequencees
Ensembl_PRO: ENSP00000304669, ENSP00000438476, ENSP00000486200, ENSP00000427821
RefSeq: NP_001310930.1, NP_001310917.1, NP_001310926.1, NP_001310914.1, NP_001310941.1, NP_001310920.1, NP_001310936.1, NP_001894.2, NP_001310942.1, NP_001277239.1, NP_001310922.1, NP_001310938.1, NP_001310939.1, NP_001277238.1, NP_001310932.1, NP_001277236.1, NP_001310916.1, NP_001310928.1, NP_001310919.1, NP_001310918.1, NP_001310937.1, NP_001310933.1, NP_001310911.1, NP_001310923.1, NP_001310924.1, NP_001310940.1, NP_001310921.1, NP_001310929.1, NP_001310913.1, NP_001310927.1, NP_001310925.1, NP_001310934.1, NP_001310912.1, NP_001310931.1, NP_001277241.1, NP_001310915.1, NP_001310935.1
Others
UniRef100: UniRef100_B4DU00, UniRef100_P35221, UniRef100_G3XAM7
UniRef90: UniRef90_G3XAM7, UniRef90_P35221
UniRef50: UniRef50_P35221
UniGene: Hs.445981, Hs.656653
CCDS: CCDS75315.1, CCDS34243.1

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