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Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

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Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

A proteome-scale map of the human interactome network.

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A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

Cell     Mikko Taipale , George Tucker , Jian Peng , Irina Krykbaeva , Zhen-Yuan Lin , Brett Larsen , Hyungwon Choi , Bonnie Berger , Anne-Claude Gingras , Susan Lindquist

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Cell     Mikko Taipale , Irina Krykbaeva , Martina Koeva , Can Kayatekin , Kenneth D Westover , Georgios I Karras , Susan Lindquist

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Identifying and characterizing a novel protein kinase STK35L1 and deciphering its orthologs and close-homologs in vertebrates.

PLoS One     Pankaj Goyal , Antje Behring , Abhishek Kumar , Wolfgang Siess

The DNA sequence and biological annotation of human chromosome 1.

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