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14940 Gzmc

14940

Gzmc

granzyme C

protein-coding

Mus musculus

基因描述

Type Description
Definition granzyme C

研究结论

Date Results Publications
2010-01-21 00:00:00 some cytolytic T lymphocytes mature into perforin/granzyme-expressing effector cells in the mediastinal lymph node and are detectable when they accumulate in lung infection 12601154
2010-01-21 00:00:00 granzyme C is activated with persistent antigenic stimulation, providing nonredundant backup protection for the host when granzyme B fails. 19414782
2010-01-21 00:00:00 IL-2 increased the expression of perforin and granzyme A, B, and C mRNA; induction of granzyme A, B, and C mRNA required exogenous IL-2, whereas induction of perforin and IFN-gamma expression did not. 16339537
2010-01-21 00:00:00 during late primary alloimmune responses, granzyme C can support CTL-mediated killing by the granule exocytosis pathway in the absence of functional granzymes A or B. 19017970
2010-01-21 00:00:00 the genes for perforin, the three major T cell granzymes (A-C) and IFN-gamma are differentially expressed during primary activation of naive CD8(+) T cells, kinetically and at the single-cell level 12039912

名称对应

Type IDs
Synonymous AI323531, B10, CCP2, Ctla-5, Ctla5
Gene
UniProtKB-ID: GRAC_MOUSE, Q0VB76_MOUSE
UniprotKB: P08882, Q0VB76
UniParc: UPI00000213D5
EMBL: M12301, M18459, X12822, BC120757, BC145030, BC120755, M22527
Ensembl: ENSMUSG00000079186
KO: mmu:14940
Nucleutide sequences
EMBL-CDS: AAA37384.1, AAA37734.1, AAA85454.1, CAA31309.1, AAI20756.1, AAI45031.1, AAI20758.1
Ensembl_TRS: ENSMUST00000015585
Protein sequencees
Ensembl_PRO: ENSMUSP00000015585
RefSeq: XP_006518631.1, NP_034501.2, XP_011243265.1
Others
UniRef100: UniRef100_P08882
UniRef90: UniRef90_P08882
UniRef50: UniRef50_P08882
UniGene: Mm.14465
CCDS: CCDS27146.1

全选

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