| Type | Description |
|---|---|
| Definition | exocyst complex component 8 |
| Date | Results | Publications |
|---|---|---|
| 2013-03-23 11:08:00 | We identified interactions between RalA and its effectors sec5 and exo84 in the Exocyst complex as directly necessary for migration and invasion of prostate cancer tumor cells. | 22761837 |
| 2010-06-28 12:08:00 | shRNA-mediated knockdown of the Ral effector proteins Sec5 and Exo84, but less so in the case of RalBP1, reduced oncogenic RalGEF-mediated transformation and oncogenic Ras-driven tumorigenic growth of human cells. | 20145037 |
| 2010-01-21 00:00:00 | evidence that mammalian exocyst components are present as distinct subcomplexes on vesicles and the plasma membrane and that Ral GTPases regulate the assembly interface of a full octameric exocyst complex through interaction with Sec5 and Exo84 | 14525976 |
| Type | IDs |
|---|---|
| Synonymous | EXO84, Exo84p, SEC84 |
| Gene |
UniProtKB-ID:
EXOC8_HUMAN
UniprotKB:
Q8IYI6
UniParc:
UPI000006EA2C
EMBL:
CH471098,
AL117352,
AK096460,
BC035763
Ensembl:
ENSG00000116903
KO:
hsa:149371
|
| Nucleutide sequences |
EMBL-CDS:
BAG53295.1,
AAH35763.2,
EAW69955.1
Ensembl_TRS:
ENST00000366645
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355605
RefSeq:
NP_787072.2
|
| Others |
UniRef100:
UniRef100_Q8IYI6
UniRef90:
UniRef90_Q8IYI6
UniRef50:
UniRef50_Q8IYI6
UniGene:
Hs.356198
CCDS:
CCDS1593.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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