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14936 Gys1

14936

Gys1

glycogen synthase 1, muscle

protein-coding

Mus musculus

基因描述

Type Description
Definition glycogen synthase 1, muscle

研究结论

Date Results Publications
2017-04-29 11:02:00 These results demonstrate that pharmacological agents that activate GYS1, the main GS subtype found in skeletal muscle, have potential for use as novel treatments for diabetes that improve glucose metabolism in skeletal muscle. 28290602
2014-02-22 10:09:00 We show that the absence of Epm2aip1 in mice impairs allosteric activation of GS by glucose 6-phosphate, decreases hepatic glycogen synthesis, increases liver fat, causes hepatic insulin resistance, and protects against age-related obesity 24142699
2013-11-02 10:58:00 Muscle glycogen synthase isoform is responsible for testicular glycogen synthesis: glycogen overproduction induces apoptosis in male germ cells. 23386391
2013-05-25 10:32:00 Long-term potentiation (LTP) evoked in the hippocampal CA3-CA1 synapse was also decreased in behaving GYS1(Nestin-KO) mice. 23281428
2012-02-25 11:09:00 Neurodegeneration and functional impairments are associated with glycogen synthase accumulation in the mouse model of Lafora disease. 21882344

名称对应

Type IDs
Synonymous Gys3, MGS
Gene
UniProtKB-ID: GYS1_MOUSE
UniprotKB: Q9Z1E4
UniParc: UPI0000020D9B
EMBL: AK050813, CH466603, AK171148, U53218, X94616, BC131687, BC131688, BC152550, BC019389
Ensembl: ENSMUSG00000003865
KO: mmu:14936
Nucleutide sequences
EMBL-CDS: EDL22855.1, AAI31689.1, AAH19389.1, CAA64322.1, BAE42275.1, AAI52551.1, BAC34420.1, AAI31688.1, AAD09457.1
Ensembl_TRS: ENSMUST00000003964
Protein sequencees
Ensembl_PRO: ENSMUSP00000003964
RefSeq: NP_109603.2
Others
UniRef100: UniRef100_Q9Z1E4
UniRef90: UniRef90_P13834
UniRef50: UniRef50_P13807
UniGene: Mm.275654
CCDS: CCDS21244.1

全选

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