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14924 Magi1

14924

Magi1

membrane associated guanylate kinase, WW and PDZ domain containing 1

protein-coding

Mus musculus

基因描述

Type Description
Definition membrane associated guanylate kinase, WW and PDZ domain containing 1

研究结论

Date Results Publications
2020-07-04 12:33:00 Study in mouse model of atherosclerosis suggests that MAGI1 simultaneously regulates endothelial cells activation and endoplasmic reticulum stress-induced apoptosis, which are critical molecular events for atherogenesis, via MAGI1-S741 phosphorylation by p90RSK and sentrin/SUMO-specific protease 2 T368 phosphorylation-mediated MAGI1-K931 deSUMOylation. 30944250
2017-05-27 11:52:00 the interaction between nephrin and MAGI-1 regulates Rap1 activation in podocytes to maintain long term slit diaphragm structure 27707879
2014-06-16 10:02:00 Cx32 expression is in part related to induction of tight junctions through modulation of Magi1 expression in an immortalized hepatic cell line. 15558322
2013-08-31 12:09:00 ARIP1 and ARIP2 are co-expressed in some nerve cells and their biological activities are distinct. 23523645
2010-09-06 12:21:00 Data conclude that the up-regulation of sdk-1 in podocytes is an important pathogenic factor in glomerulosclerosis and that the mechanism involves disruption of the actin cytoskeleton possibly via alterations in MAGI-1 function. 20562105

名称对应

Type IDs
Synonymous AIP3, BAP1, Baiap1, Gukmi1, MAGI1c, Magi-1, TNRC19, WWP3, mKIAA4129
Gene
UniProtKB-ID: MAGI1_MOUSE, Q4H4B4_MOUSE, E9PZ12_MOUSE, Q3TQ86_MOUSE, Q8CCP7_MOUSE, A0A0R4J0S6_MOUSE, Q4H4B5_MOUSE, A0A0N4SWH0_MOUSE, A0A0N4SUZ0_MOUSE
UniprotKB: Q6RHR9, Q4H4B4, E9PZ12, Q3TQ86, Q8CCP7, A0A0R4J0S6, Q4H4B5, A0A0N4SWH0, A0A0N4SUZ0
UniParc: UPI0000F54B2D, UPI0000553003, UPI0000443FAE, UPI00000E9346, UPI0000553002, UPI00005B1FD1, UPI0000F54B2F, UPI000035D974, UPI0003C41461, UPI0000028160, UPI00001C3932
EMBL: AF027503, AC138381, AF027504, AF027505, AC155649, AC160062, AK032350, AB194412, AC153601, AB194411, AK163800, AC162382, AY497557, AC101349
Ensembl: ENSMUSG00000045095
KO: mmu:14924
Nucleutide sequences
EMBL-CDS: AAS77818.1, AAB91997.1, AAB91995.1, AAB91996.1, BAE07185.1, BAE37498.1, BAC27828.1, BAE07184.1
Ensembl_TRS: ENSMUST00000089317, ENSMUST00000093769, ENSMUST00000055224, ENSMUST00000203688, ENSMUST00000204347
Protein sequencees
Ensembl_PRO: ENSMUSP00000086730, ENSMUSP00000091283, ENSMUSP00000062085, ENSMUSP00000145515, ENSMUSP00000144881
RefSeq: XP_036021771.1, XP_036021761.1, XP_017176888.1, NP_001273717.1, XP_006505652.1, XP_006505655.1, XP_030111041.1, XP_030111040.1, XP_036021769.1, XP_030111036.1, XP_036021772.1, XP_006505657.1, NP_001076790.1, XP_006505656.1, XP_006505661.1, XP_006505649.1, XP_006505647.1, XP_006505659.1, XP_036021766.1, XP_036021763.1, XP_006505646.1, XP_030111043.1, XP_006505645.1, NP_001076789.1, XP_006505644.1, NP_001273713.1, XP_036021760.1, XP_006505650.1, XP_036021768.1, NP_034497.1, NP_001025021.1, XP_006505660.1, XP_030111039.1, XP_030111044.1, XP_006505648.1, XP_006505643.1, XP_006505651.1, NP_001273715.1, XP_006505662.1, XP_036021764.1, XP_036021762.1, XP_006505664.1, XP_030111046.1, XP_006505653.1, XP_006505654.1, XP_036021767.1, XP_036021770.1, XP_006505658.1, XP_006505663.1, NP_001273714.1, XP_036021765.1, XP_017176889.1
Others
UniRef100: UniRef100_Q6RHR9, UniRef100_A0A0R4J0S6, UniRef100_A0A0N4SWH0, UniRef100_E9PZ12, UniRef100_Q4H4B5, UniRef100_Q8CCP7, UniRef100_Q4H4B4, UniRef100_Q3TQ86, UniRef100_A0A0N4SUZ0
UniRef90: UniRef90_Q6RHR9, UniRef90_A0A0N4SWH0, UniRef90_Q96QZ7-5, UniRef90_Q8CCP7, UniRef90_E9PZ12, UniRef90_Q4H4B4, UniRef90_A0A0R4J0S6, UniRef90_Q5DTM1
UniRef50: UniRef50_Q96QZ7-5, UniRef50_Q96QZ7-4, UniRef50_Q96QZ7, UniRef50_Q6RHR9-2, UniRef50_A0A6I8RNK2
UniGene: Mm.217216
CCDS: CCDS20377.1

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