| Type | Description |
|---|---|
| Definition | p40 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:49:00 | Intragenic recruitment of NF-kappaB drives splicing modifications upon activation by the oncogene Tax of HTLV-1. | 32546717 |
| 2020-05-02 10:48:00 | These findings suggest that both Tax and HBZ can alter the expression of EOS through undetermined mechanisms, and dysregulated expression of EOS in peripheral blood mononuclear leukocytes of HTLV-1 infected individuals may contribute to the pathological progression of HTLV-1-associated diseases. | 31856855 |
| 2020-04-11 12:42:00 | These findings allude to a mechanism whereby NF-kappaB-signaling regulates tubulin dynamics and mitotic instability through the modulation of p65(RelA)-Stathmin/Op-18 interactions, and support the notion that p30(II) enhances the survival of Tax-expressing HTLV-1-transformed cells. | 31299491 |
| 2019-12-14 10:11:00 | HTLV-1 Tax-1 alters GLUT1 localization via its interaction with SNX27. We demonstrate that over expression of Tax-1 in cells causes a reduction of GLUT1 on the plasma membrane. Furthermore, we show that knockdown of SNX27 results in increased virion release and decreased HTLV-1 infectivity. | 30897179 |
| 2019-02-02 10:33:00 | that IL29, IL28B, and IL28R interfere in the infection of HTLV-1-associated myelopathy/tropical spastic paraparesis, mainly via Tax activation | 29990995 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TAX_HTL1C
UniprotKB:
P14079
UniParc:
UPI000010452F
EMBL:
D13784,
AF033817
KO:
vg:1491938
|
| Nucleutide sequences |
EMBL-CDS:
AAC82583.1
|
| Protein sequencees |
RefSeq:
NP_057864.1
|
| Others |
UniRef100:
UniRef100_P14079
UniRef90:
UniRef90_P14079
UniRef50:
UniRef50_P14079
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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