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14916 Guca2b

14916

Guca2b

guanylate cyclase activator 2b (retina)

protein-coding

Mus musculus

基因描述

Type Description
Definition guanylate cyclase activator 2b (retina)

研究结论

Date Results Publications
2018-12-29 10:19:00 Guanylin and uroguanylin, as well as their prohormones, do not seem to play a significant role in body weight regulation and glycemic control, suggesting that guanylin-family peptides do not show promise as targets for the treatment of obesity or diabetes. 29289697
2017-07-08 13:04:00 guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage 27246004
2016-12-17 11:53:00 In obese mice UGN expression was decreased, whereas leptin treatment up-regulated UGN levels in duodenum in these genetically modified mice compared to WT. 25743370
2012-07-21 11:25:00 UGN exerts its inhibitory activity on the prendrin gene promoter likely via heat shock factor 1 action at a defined heat shock element site. 22129966
2010-01-21 00:00:00 Role for uroguanylin in fluid homeostasis and as an integral component of a signaling mechanism that mediates changes in Na excretion in response to an enteral salt loading. 16819406

名称对应

Type IDs
Synonymous AV066530, Gcap2, Ugn
Gene
UniProtKB-ID: GUC2B_MOUSE, Q9QUQ3_MOUSE
UniprotKB: O09051, Q9QUQ3
UniParc: UPI00000019DA
EMBL: AK002364, U90727, U95182, U67800, BC024373, AF006668
Ensembl: ENSMUSG00000032978
KO: mmu:14916
Nucleutide sequences
EMBL-CDS: AAB53314.1, AAB82750.2, BAB22042.1, AAD09311.1, AAD09215.1, AAH24373.1
Ensembl_TRS: ENSMUST00000044426
Protein sequencees
Ensembl_PRO: ENSMUSP00000043203
RefSeq: NP_032217.2
Others
UniRef100: UniRef100_O09051
UniRef90: UniRef90_P70668
UniRef50: UniRef50_P70668
UniGene: Mm.278
CCDS: CCDS18587.1

全选

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