| Type | Description |
|---|---|
| Definition | ring finger and CCCH-type domains 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:29:00 | MAP7 interacts with RC3H1 and cooperatively regulate cell-cycle progression of cervical cancer cells via activating the NF-kappaB signaling. | 32446391 |
| 2020-09-19 16:27:00 | Structural basis for the recognition of transiently structured AU-rich elements by Roquin. | 32491174 |
| 2020-04-11 10:48:00 | Transcriptome profiling revealed Roquin-dependent global downregulation of proinflammatory cytokines and antiviral genes in by human cytomegalovirus infected cells. IFN regulatory factor 1 (IRF1), a master transcriptional activator of immune responses, identified as a Roquin target gene. Roquin reduces IRF1 expression by directly binding to its mRNA, thereby enabling suppression of a variety of antiviral genes. | 31451648 |
| 2019-07-20 12:09:00 | analysis of previously unknown cis-regulatory elements in Roquin protein | 30295819 |
| 2018-02-24 10:30:00 | Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA. | 29352114 |
| Type | IDs |
|---|---|
| Synonymous | RNF198, ROQUIN |
| Gene |
UniProtKB-ID:
RC3H1_HUMAN,
B9EGU6_HUMAN,
B7ZMB3_HUMAN
UniprotKB:
Q5TC82,
B9EGU6,
B7ZMB3
UniParc:
UPI0000576826,
UPI00001D7DA8,
UPI000189A8A1,
UPI0000418ECA
EMBL:
AL121983,
BC136784,
AB095945,
AL136170,
AK093501,
AK122948,
BC144408
Ensembl:
ENSG00000135870
KO:
hsa:149041
|
| Nucleutide sequences |
EMBL-CDS:
BAG53813.1,
BAC04186.1,
BAC23121.1,
AAI36785.1,
AAI44409.1
Ensembl_TRS:
ENST00000367694,
ENST00000367696,
ENST00000258349
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258349,
ENSP00000356669,
ENSP00000356667
RefSeq:
NP_001287780.1,
NP_001287779.1,
XP_005244978.1,
NP_742068.1,
XP_011507533.1,
NP_001287781.1
|
| Others |
UniRef100:
UniRef100_B7ZMB3,
UniRef100_Q5TC82,
UniRef100_B9EGU6
UniRef90:
UniRef90_Q5TC82
UniRef50:
UniRef50_Q5TC82
UniGene:
Hs.30258
CCDS:
CCDS30940.1,
CCDS72987.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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