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1489081 L2

1489081

L2

minor capsid protein L2

protein-coding

Human papillomavirus type 16

基因描述

Type Description
Definition minor capsid protein L2

研究结论

Date Results Publications
2020-06-06 13:58:00 By confocal analysis, it was determined that nuclear entry of assembled L1 is dependent upon the presence of the minor capsid protein, L2, but independent of encapsidated DNA. 31092566
2019-09-28 10:41:00 findings demonstrate that gamma-secretase is endowed with an activity that can promote membrane insertion of L2, thereby targeting the virus to the productive infectious pathway. 30006461
2018-12-01 10:13:00 The authors show that stannin interacts with human papillomavirus 16 L1 major capsid protein and impairs the interaction of the L2 minor capsid protein with retromer, which is required for virus trafficking to the trans-Golgi network. 29058661
2017-10-07 12:42:00 The HPV-16 structures clarify details of capsid architecture for the first time, including variation in L1 major capsid protein conformation and putative location of L2 minor protein. 28065506
2017-10-07 11:19:00 The data suggest a common strategy among various papillomaviruses (PVs), in which a central region of L2 mediates tethering of vDNA to mitotic chromosomes during cell division thereby coordinating membrane translocation and delivery to daughter nuclei. 28464022

名称对应

Type IDs
Gene
UniProtKB-ID: A0A220NMU2_HPV16, A0A166MB26_9PAPI
UniprotKB: A0A220NMU2, A0A166MB26
UniParc: UPI000004B6A0
EMBL: MG850386, MG848611, MG850681, KY549218, MG848332, KU053855
KO: vg:1489081
Nucleutide sequences
EMBL-CDS: AVN73814.1, ASJ77952.1, AVN84098.1, AVN82758.1, AVN72331.1, ANA51144.1
Protein sequencees
RefSeq: NP_041331.2
Others
UniRef100: UniRef100_A0A220NMU2
UniRef90: UniRef90_P03107
UniRef50: UniRef50_P03107

全选

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研究热度

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