| Type | Description |
|---|---|
| Definition | general transcription factor II H, polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2014-06-07 10:18:00 | Mice with a liver overexpression of insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IMP2-2/IGF2BP2-2 show elevated Ccl2 levels, which models all stages of non-alcoholic fatty liver disease. | 24173291 |
| 2013-12-14 11:52:00 | We propose that autophagy is inhibited in the alphaB-R120G mutant lenses because of a defect in protein degradation after autophagosome formation. | 23872361 |
| 2011-09-24 11:51:00 | p62 is up-regulated in mouse proteinopathic hearts and promotes aggresome formation and autophagy activation and protects cardiomyocytes against proteotoxic stress | 21659648 |
| 2011-01-29 10:36:00 | cdk1 phosphorylates p62 in vitro and in vivo at T269 and S272, which is necessary for the maintenance of appropriate cyclin B1 levels and the levels of cdk1 activity necessary to allow cells to properly enter and exit mitosis. | 20974803 |
| 2010-08-09 11:16:00 | p62 is a crucial regulator of ERK1 in metabolism | 20154642 |
| Type | IDs |
|---|---|
| Synonymous | 62kDa, AW743425, AW822074, BTF2 p62, C77871, p62 |
| Gene |
UniProtKB-ID:
TF2H1_MOUSE,
Q7TPY0_MOUSE,
G3X8R4_MOUSE,
E9QKD9_MOUSE
UniprotKB:
Q9DBA9,
Q7TPY0,
G3X8R4,
E9QKD9
UniParc:
UPI00000282A3,
UPI00015AA46D,
UPI000019C78E,
UPI0000020FA8
EMBL:
BC052837,
AJ002366,
AC090122,
AC090123,
AK005065
Ensembl:
ENSMUSG00000006599
KO:
mmu:14884
|
| Nucleutide sequences |
EMBL-CDS:
CAA05340.1,
BAB23789.1,
AAH52837.1
Ensembl_TRS:
ENSMUST00000006774,
ENSMUST00000107644
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000006774,
ENSMUSP00000103271
RefSeq:
NP_001278004.1,
NP_032212.3,
NP_001347005.1,
NP_001347004.1
|
| Others |
UniRef100:
UniRef100_E9QKD9,
UniRef100_G3X8R4,
UniRef100_Q9DBA9
UniRef90:
UniRef90_Q9DBA9
UniRef50:
UniRef50_P32780
UniGene:
Mm.22700
CCDS:
CCDS21287.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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