| Type | Description |
|---|---|
| Definition | tegument protein; phosphorylates nuclear egress lamina protein; mediates phosphorylation of HDAC1 and HDAC2 and other cellular and viral proteins; involved in protein phosphorylation; involved in apoptosis; involved in nuclear egress |
| Date | Results | Publications |
|---|---|---|
| 2016-04-30 10:05:00 | The difference between HSV-1 and HSV-2 Us3 kinases appeared to be due to the fact that some Us3 phosphorylation sites in HSV-1 proteins are not conserved in the corresponding HSV-2 proteins. | 26491159 |
| 2011-07-16 11:30:00 | These findings demonstrate that Us3 orthologues derived from distantly related alphaherpesviruses cause a disruption of PML protein nuclear bodies in a kinase- and proteasome-dependent manner but, do not target PML for degradation. | 21430051 |
| 2010-02-22 12:26:00 | Herein the authors describe determinants of HSV-2 Us3-induced filamentous processes formation and present evidence for the presence of a leucine-rich nuclear export signal within HSV-2 Us3. | 19945726 |
| 2010-01-21 00:00:00 | required for stable expression of UL46 and its association with virions, and phosphorylates Ul46 in vitro | 15958677 |
| 2010-01-21 00:00:00 | These results suggest that the US3 protein kinase of HSV regulates virus-induced neuronal apoptosis in peripheral conduits and determines the neuroinvasive phenotype of HSV. | 16815072 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
G9I285_HHV2
UniprotKB:
G9I285
UniParc:
UPI000240D4EC
EMBL:
MH790659,
MH790620,
MF564037,
KX574863,
MH790617,
MH790577,
MH790552,
MH790589,
MH790587,
KX574893,
MF564035,
MH790655,
MH790647,
MN187895,
KX574871,
MH790591,
KX574872,
KX574884,
KX574880,
MF564034,
KX574908,
MH790636,
KX574890,
KX574900,
MH790639,
MF564036,
KP334095,
MK105999,
KX574867,
KX574864,
MH790553,
KX574874,
MH790590,
MH790599,
MH790648,
KX574861,
MH790554,
MH790632,
MH790633,
MH790555,
KX574904,
KX574897,
MH790605,
MH790573,
KU310662,
MH790618,
MF621258,
MH790601,
MH790640,
MH899846,
KX574882,
MH790613,
KX574889,
MH790595,
MK105997,
MH790612,
MH790656,
MH790630,
MF621257,
KY922724,
MH790558,
MH790566,
MH790625,
MH790565,
MH790650,
KX574866,
MH790626,
KX574899,
MH790604,
MK106001,
MH790616,
MH790666,
JN561323,
MH790607
KO:
vg:1487355
|
| Nucleutide sequences |
EMBL-CDS:
QBH84314.1,
QBH81033.1,
QBH80285.1,
QBH82653.1,
QBH79970.1,
AQZ57171.1,
QBH77072.1,
AQZ58875.1,
QBH81290.1,
QBH81368.1,
QBH81633.1,
AQZ57455.1,
QBH85080.1,
AQZ55964.1,
QBH78825.1,
ATD86645.1,
QBH75891.1,
QBH79166.1,
AQZ55822.1,
AQZ58094.1,
AQZ58378.1,
AQZ56532.1,
QBH75808.1,
QAU10835.1,
QBH77917.1,
AWP48731.1,
ATB17378.1,
QBH82488.1,
AQZ57810.1,
AQZ57881.1,
ATB17454.1,
AWP48656.1,
QBH83358.1,
AQZ59159.1,
QBH76062.1,
QBH82147.1,
QBH76989.1,
QBH76386.1,
QBH77662.1,
QBH84069.1,
QBH82733.1,
QBH80954.1,
AQZ56603.1,
QBH84147.1,
QBH83089.1,
AQZ56035.1,
QBH79086.1,
ATB17530.1,
QBH82057.1,
AQZ58520.1,
QBH81462.1,
QAU10544.1,
AQZ56745.1,
QBH85819.1,
AQZ58591.1,
QBH79432.1,
QIH12387.1,
QBH80370.1,
QBH87561.1,
QBH80528.1,
QBH78989.1,
AQZ57313.1,
AQZ56177.1,
QAU10691.1,
QBH84765.1,
AEV91402.1,
QBH84842.1,
AQZ56248.1,
AKC59444.1,
QBH75969.1,
AMB66025.1,
ATB17606.1,
QBH83454.1,
QBH79779.1
|
| Protein sequencees |
RefSeq:
YP_009137215.1
|
| Others |
UniRef100:
UniRef100_G9I285
UniRef90:
UniRef90_P13287
UniRef50:
UniRef50_P04413
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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