| Type | Description |
|---|---|
| Definition | glutathione S-transferase omega 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 12:39:00 | The potential therapeutic utility of GSTO1-1 inhibitors in the modulation of inflammation. | 29259211 |
| 2019-04-20 10:28:00 | These results indicate that GSTO1-1 is required for inflammatory-mediated photoreceptor death in retinal degenerations. Targeting GSTO1-1 may be a useful strategy to reduce oxidative stress and inflammation and ameliorate photoreceptor loss, slowing the progression of retinal degenerations. | 30193308 |
| 2016-04-09 11:37:00 | Data indicate that GSTO1-1 is required for LPS-mediated signalling in macrophages and that it acts early in the LPS-TLR4 pro-inflammatory pathway. | 25908843 |
| 2015-05-16 12:05:00 | shRNA knockdown of GSTO1-1 in macrophage-like J774.1A cells blocks the expression of NADPH oxidase 1 and the generation of reactive oxygen species after Bacterial lipopolysaccharide stimulation. | 24873723 |
| 2010-08-16 11:24:00 | Genes encoding the antioxidants GPX2 and GSTO 1-1 are common inflammatory genes expressed upon induction of allergic airway inflammation, and independently of allergic susceptibility. | 19897562 |
| Type | IDs |
|---|---|
| Synonymous | AA407097, AI194287, AU018802, Gsto-1, Gstx, Spg-r, p28 |
| Gene |
UniProtKB-ID:
GSTO1_MOUSE
UniprotKB:
O09131
UniParc:
UPI0000003F4F
EMBL:
U80819,
AK027922,
BC085165,
AK146834,
AK168383
Ensembl:
ENSMUSG00000025068
KO:
mmu:14873
|
| Nucleutide sequences |
EMBL-CDS:
AAB70110.1,
BAE40311.1,
BAC25667.1,
AAH85165.1,
BAE27469.1
Ensembl_TRS:
ENSMUST00000026050
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026050
RefSeq:
NP_034492.1
|
| Others |
UniRef100:
UniRef100_O09131
UniRef90:
UniRef90_O09131
UniRef50:
UniRef50_P78417-2
UniGene:
Mm.378931
CCDS:
CCDS29893.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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