| Type | Description |
|---|---|
| Definition | PHD finger protein 13 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-28 10:29:00 | High SPOC1 expression is associated with Cytomegalovirus infections. | 29743358 |
| 2018-06-09 11:40:00 | PHF13 has opposing effects throughout the HIV-1 replication cycle (figure 8). After viral entry and nuclear import of the PIC, PHF13 can increase the number of integrated HIV-1 proviral genomes. After integration, PHF13 acts as antiviral restriction factor and inhibits viral gene expression. | 29021215 |
| 2017-11-18 11:49:00 | These experiments showed that PHF13 binds specifically to DNA and to two types of histone H3 methyl tags (lysine 4-tri-methyl or lysine 4-di-methyl) where it functions as a transcriptional co-regulator. | 27223324 |
| 2014-06-28 10:21:00 | SPOC1-mediated restriction imposed upon Ad growth is relieved by its functional association with the Ad major core protein pVII that enters with the viral genome, followed by E1B-55K/E4orf6-dependent proteasomal degradation of SPOC1. | 24278021 |
| 2010-01-21 00:00:00 | SPOC1 modulates chromatin structure and that tight regulation of its expression levels and subcellular localization during mitosis are crucial for proper chromosome condensation and cell division. | 19638409 |
| Type | IDs |
|---|---|
| Synonymous | PHF5, SPOC1 |
| Gene |
UniProtKB-ID:
PHF13_HUMAN,
A0A158RFV6_HUMAN
UniprotKB:
Q86YI8,
A0A158RFV6
UniParc:
UPI000013C9BF
EMBL:
BC032792,
AL121733,
BC038516,
AL031447,
AB209544,
AY069975,
CH471130,
AK097715,
AK315110
Ensembl:
ENSG00000116273
KO:
hsa:148479
|
| Nucleutide sequences |
EMBL-CDS:
BAG37568.1,
BAG53519.1,
AAH32792.2,
CAB57324.1,
AAH38516.1,
BAD92781.1,
EAW71561.1,
AAL58478.1
Ensembl_TRS:
ENST00000377648
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366876
RefSeq:
NP_722519.2,
XP_011539064.1
|
| Others |
UniRef100:
UniRef100_Q86YI8
UniRef90:
UniRef90_Q86YI8
UniRef50:
UniRef50_Q86YI8
UniGene:
Hs.516079
CCDS:
CCDS85.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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