| Type | Description |
|---|---|
| Definition | granulin |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:37:00 | Progranulin suppresses the age-dependent enhancement of neuronal activity in the hypothalamus. | 31945450 |
| 2021-04-13 10:10:00 | PGRN exerts inflammatory effects via SIRT1-NF-kappaB in adipose insulin resistance. | 31990656 |
| 2021-02-13 13:23:00 | Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. | 32866962 |
| 2021-01-23 12:58:00 | Progranulin deficiency leads to enhanced age-related cardiac hypertrophy through complement C1q-induced beta-catenin activation. | 31866375 |
| 2021-01-02 12:53:00 | PGRN(-/-) TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration. | 33181174 |
| Type | IDs |
|---|---|
| Synonymous | GP88, PCDGF, PEPI, Pgrn, epithelin |
| Gene |
UniProtKB-ID:
GRN_MOUSE,
Q544Y8_MOUSE,
Q9D2V3_MOUSE,
Q3U9N4_MOUSE
UniprotKB:
P28798,
Q544Y8,
Q9D2V3,
Q3U9N4
UniParc:
UPI00000E8820,
UPI0000003F0D,
UPI00005664E1
EMBL:
AK159428,
AK152213,
AK152118,
M86736,
AK152765,
AK160033,
D16195,
BC129850,
AK151007,
AK160074,
AK152087,
AK013678,
AK152944,
X62321,
AK151713,
AK154492,
AK018744,
AK150420,
AL596258,
BC129849,
AK150338,
AK152705,
AK153289,
AK153418
Ensembl:
ENSMUSG00000034708
KO:
mmu:14824
|
| Nucleutide sequences |
EMBL-CDS:
BAA03736.1,
AAA37191.1,
CAA44197.1,
BAE35608.1,
BAE29480.1,
BAE35075.1,
BAB28951.1,
BAE29544.1,
AAI29851.1,
AAI29850.1,
BAE30962.1,
BAE31041.1,
BAE31615.1,
BAB31384.2,
BAE30632.1,
BAE31433.1,
BAE31478.1,
BAE31978.1,
BAE35576.1,
BAE31872.1,
BAE30937.1,
BAE32624.1,
BAE30030.1
Ensembl_TRS:
ENSMUST00000239431,
ENSMUST00000049460
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000159379,
ENSMUSP00000046340
RefSeq:
NP_032201.3
|
| Others |
UniRef100:
UniRef100_Q9D2V3,
UniRef100_P28798
UniRef90:
UniRef90_P28798
UniRef50:
UniRef50_P28799
UniGene:
Mm.1568
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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