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1482 NKX2-5

1482

NKX2-5

NK2 homeobox 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition NK2 homeobox 5

研究结论

Date Results Publications
2021-03-13 13:23:00 Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface. 32681840
2021-02-20 13:29:00 Cardiac specific transcription factor Csx/Nkx2.5 regulates transient-outward K(+) channel expression in pluripotent P19 cell-derived cardiomyocytes. 32213161
2021-01-23 13:01:00 Axenfeld-Rieger syndrome-associated mutants of the transcription factor FOXC1 abnormally regulate NKX2-5 in model zebrafish embryos. 32631953
2021-01-02 12:53:00 Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5. 33035436
2020-05-23 13:19:00 pacemaker cardiomyocytes derive from a subset of Nkx2.5+ mesoderm that responds to canonical Wnt5b signaling to initiate the cardiac pacemaker program 31402282

名称对应

Type IDs
Synonymous CHNG5, CSX, CSX1, HLHS2, NKX2.5, NKX2E, NKX4-1, VSD3
Gene
UniProtKB-ID: NKX25_HUMAN, A0A0S2Z383_HUMAN, E5RH49_HUMAN, A0A0S2Z3K2_HUMAN
UniprotKB: P52952, A0A0S2Z383, E5RH49, A0A0S2Z3K2
UniParc: UPI00004DF3FB, UPI0000062197, UPI00017A779A, UPI0001E8F27A
EMBL: AK309495, KU178001, CH471062, KU178002, AC008412, U34962, AK290615, BC025711, AB021133, AK297844
Ensembl: ENSG00000183072
KO: hsa:1482
Nucleutide sequences
EMBL-CDS: BAG60178.1, BAA35181.1, EAW61404.1, BAF83304.1, AAC50470.1, AAH25711.1, ALQ33459.1, ALQ33460.1
Ensembl_TRS: ENST00000521848, ENST00000329198, ENST00000424406, ENST00000517440
Protein sequencees
Ensembl_PRO: ENSP00000427906, ENSP00000395378, ENSP00000327758, ENSP00000429905
RefSeq: NP_001159648.1, XP_016864560.1, NP_004378.1, NP_001159647.1
Others
UniRef100: UniRef100_A0A0S2Z3K2, UniRef100_P52952
UniRef90: UniRef90_A0A0S2Z3K2, UniRef90_P52952
UniRef50: UniRef50_F6UR19, UniRef50_P52952
UniGene: Hs.54473
CCDS: CCDS54950.1, CCDS54949.1, CCDS4387.1

全选

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