| Type | Description |
|---|---|
| Definition | glutamate receptor, ionotropic, AMPA4 (alpha 4) |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 10:21:00 | Frrsl1 deletion results in an increased proportion of immature AMPA receptors, indicated by incomplete glycosylation of GLUA2 (also known as GRIA2) and GLUA4 (also known as GRIA4) AMPA receptor proteins. | 30692144 |
| 2019-05-11 10:57:00 | find that during the first week in culture (DIV2-6) when GluA4 expression is restricted to pyramidal neurons, loss of GluA4 has no effect on the overall excitability of the immature network | 28856535 |
| 2019-02-16 12:21:00 | Study indentifies NF-Yb as a novel transcriptional regulator of Gria4 (GluA4 gene), and a controller of excitotoxic death in the oligodendroglial lineage; describes a novel regulatory region within Gria4 containing CCAAT sequences whose binding by NF-Yb is regulated by excitotoxicity. Excitotoxicity-induced alterations in NF-Yb binding are associated with changes in Gria4 transcription. | 29704264 |
| 2018-06-23 11:39:00 | The central distribution of AMPARs is absent in GluA3-knockout mice, and gold particles are evenly distributed along the postsynaptic density. GluA4 gold labeling was homogenously distributed along both synapse types. Thus, GluA3 and GluA4 subunits are distributed at auditory nerve synapses in a target-cell-dependent manner. | 28397107 |
| 2017-09-09 11:43:00 | These data suggest that GluA4 enables efficient homeostatic upscaling and responsiveness to temporal activity patterns during the critical period of activity-dependent refinement of the circuitry. | 26961102 |
| Type | IDs |
|---|---|
| Synonymous | GluA4, GluR-D, Glur-4, Glur4, Gluralpha4, spkw1 |
| Gene |
UniProtKB-ID:
GRIA4_MOUSE,
E9PX01_MOUSE,
Q8C069_MOUSE
UniprotKB:
Q9Z2W8,
E9PX01,
Q8C069
UniParc:
UPI00002131A3,
UPI000162EC77,
UPI00000EA338
EMBL:
AB079073,
AC127269,
CT030685,
AC156503,
AK032103,
AC134592,
AB022913,
AC141562,
BC060697
Ensembl:
ENSMUSG00000025892
KO:
mmu:14802
|
| Nucleutide sequences |
EMBL-CDS:
BAE06154.1,
AAH60697.1,
BAA74538.1,
BAC27702.1
Ensembl_TRS:
ENSMUST00000063508,
ENSMUST00000163309
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000066980,
ENSMUSP00000129316
RefSeq:
NP_062665.4,
XP_006509905.1,
XP_006509904.1,
XP_011240657.1,
XP_006509907.1,
XP_006509908.1,
NP_001106652.1,
XP_006509906.1,
NP_001106651.2
|
| Others |
UniRef100:
UniRef100_Q9Z2W8,
UniRef100_Q8C069,
UniRef100_E9PX01
UniRef90:
UniRef90_P48058-2,
UniRef90_P19493
UniRef50:
UniRef50_P19493,
UniRef50_P48058-2
UniGene:
Mm.209263
CCDS:
CCDS22797.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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