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14800 Gria2

14800

Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

protein-coding

Mus musculus

基因描述

Type Description
Definition glutamate receptor, ionotropic, AMPA2 (alpha 2)

研究结论

Date Results Publications
2021-02-06 13:52:00 A new mouse line with reduced GluA2 Q/R site RNA editing exhibits loss of dendritic spines, hippocampal CA1-neuron loss, learning and memory impairments and NMDA receptor-independent seizure vulnerability. 32102661
2020-11-28 13:16:00 GRIP1 regulates synaptic plasticity and learning and memory. 32948689
2020-07-04 12:21:00 Phosphorylation at GluA2 Y876 increases GluA2 binding to GRIP1. These results demonstrate that AMPAR trafficking during homeostatic upscaling can be gated by a single phosphorylation site on the GluA2 subunit. 32071234
2020-06-20 10:59:00 GluA2-containing Ca(2+)-impermeable AMPA receptors contribute to signal transmission from photosensitive retinal cells to dopaminergic amacrine cells. 31819340
2020-03-28 11:32:00 Nanoscale mobility of resting AMPA receptors predetermines responsiveness to neurotransmitter, allosteric anions and auxiliary subunits. Mobility at rest is regulated by alternative splicing of the flip/flop cassette of the ligand-binding domain, which controls motions in the distant AMPA receptor N-terminal domain (NTD). 31053408

名称对应

Type IDs
Synonymous GluA2, GluR-B, Glur-2, Glur2, gluR-K2
Gene
UniProtKB-ID: Q4LG64_MOUSE
UniprotKB: Q4LG64
UniParc: UPI0000551A6B
EMBL: AB111957
Nucleutide sequences
EMBL-CDS: BAE06155.1
Protein sequencees
RefSeq: NP_001344856.2, NP_001034284.2, NP_001344853.2, XP_006501077.1, NP_001077275.2, NP_038568.3
Others
UniRef100: UniRef100_Q4LG64
UniRef90: UniRef90_P19491-2
UniRef50: UniRef50_P19491
UniGene: Mm.220224

全选

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研究热度

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