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14792 Lpcat3

14792

Lpcat3

lysophosphatidylcholine acyltransferase 3

protein-coding

Mus musculus

基因描述

Type Description
Definition lysophosphatidylcholine acyltransferase 3

研究结论

Date Results Publications
2021-01-23 12:58:00 ABHD12 and LPCAT3 Interplay Regulates a Lyso-phosphatidylserine-C20:4 Phosphatidylserine Lipid Network Implicated in Neurological Disease. 32364701
2020-08-22 15:31:00 The role of the small intestine in modulating metabolism and inflammation in atherosclerosis and cancer. 31356236
2020-02-01 10:32:00 LPCAT3 is depleted in non-alcoholic steatohepatitis and leads to caspase-dependent/caspase-independent cell death. 30160786
2019-10-26 10:35:00 LPCAT3 as a key factor in the control of phospholipid homeostasis and arachidonate availability in myeloid cells and its deficiency in hematopoietic cells alters cholesterol and phospholipid homeostasis and promotes atherosclerosis. 29866392
2018-12-22 11:27:00 Study show for the first time that LPCAT3 is the major isoform of LPCAT in 3T3L1 pre-adipocytes, and mature adipocytes, as well as mouse adipose tissue, and that LPCAT3 activity-mediated phosphatidylcholine (PC) remodeling affects adipocyte polyunsaturated PC composition, most likely on the cell membrane, thus influencing Wnt/beta-catenin signaling pathway and inhibiting pre-adipocyte differentiation and lipogenesis. 29673706

名称对应

Type IDs
Synonymous C3f, Grcc3f, Lpcat, Lpeat, Lplat5, Lpsat, Mboat5, Moact5, Oact5, PTG
Gene
UniProtKB-ID: MBOA5_MOUSE
UniprotKB: Q91V01
UniParc: UPI0000020DDF
EMBL: AB294194, AC002397, BC006753, AK083687, CH466523, AY028317
Ensembl: ENSMUSG00000004270
KO: mmu:14792
Nucleutide sequences
EMBL-CDS: AAH06753.2, AAC36007.1, EDK99746.1, BAG12120.1, BAC38993.1, AAK20915.1
Ensembl_TRS: ENSMUST00000004381
Protein sequencees
Ensembl_PRO: ENSMUSP00000004381
RefSeq: XP_036021746.1, XP_036021745.1, NP_660112.1
Others
UniRef100: UniRef100_Q91V01
UniRef90: UniRef90_Q91V01
UniRef50: UniRef50_Q91V01
UniGene: Mm.273915
CCDS: CCDS20523.1

全选

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