| Type | Description |
|---|---|
| Definition | cleavage stimulation factor subunit 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-27 13:14:00 | Data show that the recruitment of CstF subunit CstF-50 to CstF via interaction with cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa protein (CstF-77) and establish that the hexameric assembly of CstF. | 29186539 |
| 2019-07-27 10:55:00 | Reverse genetics and nuclear magnetic resonance studies of recombinant CstF-64 (RRM-Hinge) and CstF-77 (monkeytail-carboxy-terminal domain) indicate that the last 30 amino acids of CstF-77 increases the stability of the RRM, thus altering the affinity of the complex for RNA. These results provide new insights into the mechanism by which CstF regulates the location of the RNA cleavage site during Cleavage/polyadenylation. | 30257008 |
| 2018-07-23 13:14:00 | Results from a study on gene variability markers in early-stage human embryos shows that CSTF3 is a putative variability marker for the 3-day, 8-cell embryo stage. | 26288249 |
| 2014-01-11 11:15:00 | Thus, the conserved intronic pA of the CstF-77 gene may function as a sensor for cellular C/P and splicing activities, controlling the homeostasis of CstF-77 and C/P activity and impacting cell proliferation and differentiation. | 23874216 |
| 2011-07-23 10:31:00 | nuclear accumulation of CstF-64 depends on binding to CstF-77 not symplekin; interaction between CstF-64/CstF-64Tau and CstF-77 are important for maintenance of nuclear levels of CstF complex components and intracellular localization, stability, function | 21119002 |
| Type | IDs |
|---|---|
| Synonymous | CSTF-77 |
| Gene |
UniProtKB-ID:
CSTF3_HUMAN
UniprotKB:
Q12996
UniParc:
UPI000006ECC3,
UPI00000527FD,
UPI00005B2F04
EMBL:
BC009792,
AL121926,
AK290836,
BC059948,
BC010533,
U15782,
AC131263,
BC108319,
CH471064,
BM014288
Ensembl:
ENSG00000176102
KO:
hsa:1479
|
| Nucleutide sequences |
EMBL-CDS:
EAW68202.1,
AAH59948.1,
EAW68200.1,
AAH09792.1,
AAH10533.1,
EAW68201.1,
AAA61417.1,
BAF83525.1,
AAI08320.1,
CAC48252.1
Ensembl_TRS:
ENST00000438862,
ENST00000323959,
ENST00000431742
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000393064,
ENSP00000388711,
ENSP00000315791
RefSeq:
NP_001028677.1,
NP_001317.1,
NP_001028678.1
|
| Others |
UniRef100:
UniRef100_Q12996
UniRef90:
UniRef90_Q12996
UniRef50:
UniRef50_Q12996
UniGene:
Hs.44402
CCDS:
CCDS7883.1,
CCDS44564.1,
CCDS44563.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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