| Type | Description |
|---|---|
| Definition | SPC24 component of NDC80 kinetochore complex |
| Date | Results | Publications |
|---|---|---|
| 2018-09-22 10:16:00 | SPC24 is up-regulated in human breast cancer.SPC24 regulates PI3K/AKT kinase pathway in breast cancer. | 30180968 |
| 2017-10-14 10:28:00 | our data demonstrates that SPC24 can serve as a promising prognostic biomarker of anaplastic thyroid cancer cells | 28423533 |
| 2016-10-01 11:18:00 | Data indicate that kinetochore protein Spc24 (SPC24) may be a promising molecular target for hepatocellular carcinoma (HCC) therapy. | 26515591 |
| 2010-01-21 00:00:00 | hSPC24 is a component of the human NDC80 kinetochore complex | 14699129 |
| 2010-01-21 00:00:00 | the Spc24, Spc25, Nuf2, and Ndc80/Hec1 complex is a faithful copy of the endogenous Ndc80 complex | 15961401 |
| Type | IDs |
|---|---|
| Synonymous | SPBC24 |
| Gene |
UniProtKB-ID:
SPC24_HUMAN,
B4E086_HUMAN
UniprotKB:
Q8NBT2,
B4E086
UniParc:
UPI00017A8413,
UPI00015DF98A,
UPI00017A832C
EMBL:
AY456387,
BC105039,
AK075287,
AK303266,
AC011485,
AK303157,
BC105037
Ensembl:
ENSG00000161888
KO:
hsa:147841
|
| Nucleutide sequences |
EMBL-CDS:
BAG64259.1,
AAI05038.1,
AAR88651.1,
AAI05040.1,
BAC11523.1,
BAG64348.1
Ensembl_TRS:
ENST00000592540
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000465075
RefSeq:
XP_005259810.1,
NP_001303960.1,
NP_001303961.1,
NP_872319.1,
XP_011526004.1,
NP_001303962.1
|
| Others |
UniRef100:
UniRef100_Q8NBT2,
UniRef100_B4E086
UniRef90:
UniRef90_Q8NBT2
UniRef50:
UniRef50_Q8NBT2
UniGene:
Hs.381225
CCDS:
CCDS45974.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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