| Type | Description |
|---|---|
| Definition | G protein-coupled receptor kinase 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 13:12:00 | GRK5 deficiency contributes to the pathogenesis of Alzheimer's disease by influencing the hyperphosphorylation of tau through the activation of GSK3beta. | 30511419 |
| 2019-09-14 10:07:00 | These data indicate that GRK2, GRK5 and GRK6 redundantly modulate Smo-GATA crosstalk in fetal mouse hearts, orchestrating transcriptional pathways previously linked to clinical and experimental atrioventricular canal defects | 29969579 |
| 2019-05-11 12:55:00 | GRK5 is critical for maintaining normal mTORC1 signaling and connectivity in medial prefrontal cortex and normal social behavior. | 28334166 |
| 2018-04-14 10:30:00 | Along with other supporting evidence, the authors propose that GRK5 deficiency selectively renders basal forebrain cholinergic neurons more vulnerable to degeneration. | 27193825 |
| 2017-05-20 13:25:00 | Overall, these data suggest that GRK5 negatively regulates CXCL1/KC levels during bacterial pneumonia but that the role of GRK5 in the clinical outcome in this model is dependent on the bacterial dose. | 26975990 |
| Type | IDs |
|---|---|
| Synonymous | Gprk5 |
| Gene |
UniProtKB-ID:
GRK5_MOUSE,
Q3TST4_MOUSE
UniprotKB:
Q8VEB1,
Q3TST4
UniParc:
UPI0000027C2A
EMBL:
AF040759,
AF040746,
AK135076,
BC019379,
AF040756,
AK161821,
AF040758,
AF040755,
AF040757
Ensembl:
ENSMUSG00000003228
KO:
mmu:14773
|
| Nucleutide sequences |
EMBL-CDS:
AAC09271.1,
AAH19379.1,
AAC09267.1,
BAE36591.1,
BAE22411.1
Ensembl_TRS:
ENSMUST00000003313
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003313
RefSeq:
XP_017173555.2,
XP_006526760.1,
XP_036017332.1,
NP_061357.3,
XP_011245451.1
|
| Others |
UniRef100:
UniRef100_Q8VEB1
UniRef90:
UniRef90_P34947
UniRef50:
UniRef50_P34947
UniGene:
Mm.279400
CCDS:
CCDS29945.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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