Type | Description |
---|---|
Definition | glycosylphosphatidylinositol specific phospholipase D1 |
Date | Results | Publications |
---|---|---|
2019-11-23 12:34:00 | Mice lacking GPI-PLD exhibited the amelioration of glucose intolerance and hepatic steatosis under high-fat and high-sucrose diet. Furthermore, diacylglycerol (DAG) content was significantly decreased, and activity was suppressed in the livers of GP-KO mice. | 30457913 |
2010-10-30 10:38:00 | Overexpressing GPI-PLD in an insulinoma cell line enhanced glucose-stimulated insulin secretion, suggesting that enhanced insulin secretion in vivo may have contributed to the improved glucose tolerance. | 20153004 |
2010-01-21 00:00:00 | His29, His125, His133 and His158 are required for GPI-PLD catalytic activity | 15943582 |
2010-01-21 00:00:00 | Results suggest that cell-specific Gpld1- or peptidase-dependent pathways for prostasin secretion may control prostasin functions in a tissue-specific manner. | 16822939 |
2010-01-21 00:00:00 | Glycosylphosphatidylinositol-specific phospholipase D influences triglyceride-rich lipoprotein metabolism. | 16219662 |
Type | IDs |
---|---|
Synonymous | 6330541J12Rik, AW546131 |
Gene |
UniProtKB-ID:
Q8VCU2_MOUSE,
Q8R432_MOUSE
UniprotKB:
Q8VCU2,
Q8R432
UniParc:
UPI0000021BA0,
UPI00000E589F
EMBL:
AY081194,
BC019146,
AL589699,
AL645533
Ensembl:
ENSMUSG00000021340
KO:
mmu:14756
|
Nucleutide sequences |
EMBL-CDS:
AAH19146.1,
CAI26087.1,
AAL87452.1
Ensembl_TRS:
ENSMUST00000021773
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021773
RefSeq:
NP_032182.2,
XP_011242584.1,
XP_030103017.1
|
Others |
UniRef100:
UniRef100_Q8VCU2,
UniRef100_Q8R432
UniRef90:
UniRef90_O70362
UniRef50:
UniRef50_P80108
UniGene:
Mm.291831
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
30457913 |
Am. J. Physiol. Endocrinol. Metab. Shigeki Masuda , Yuya Fujishima , Norikazu Maeda , Yuri Tsugawa-Shimizu , Yuto Nakamura , Yoshimitsu Tanaka , Yoshinari Obata , Shiro Fukuda , Hirofumi Nagao , Shunbun Kita , Hitoshi Nishizawa , Iichiro Shimomura |
2019-02-01 | - |
27626380 |
High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray |
2016-09-22 | - |
23055941 |
PLoS Genet. Jennifer C Y Lo , Duangporn Jamsai , Anne E O'Connor , Claire Borg , Brett J Clark , James C Whisstock , Mark C Field , Vicki Adams , Tomomoto Ishikawa , R John Aitken , Belinda Whittle , Christopher C Goodnow , Christopher J Ormandy , Moira K O'Bryan |
2012-01-01 |
Xpo1,
Aldh1l1,
Cyb5r3,
Cse1l,
Ace,
Acta2,
Alpl,
Apoa1,
Apoe,
Atp6v1e1,
Cct3,
Cct6a,
Entpd2,
Ift81,
Ckb,
Clu,
Mapre1,
Eef2,
Ppm1g,
Gpld1,
Hspa5,
Hk1,
Hspa8,
Hspa2,
Hsp90ab1,
Hsp90aa1,
Hspa4,
Kpnb1,
Ldhc,
Lta4h,
Slc3a2,
Me1,
Nudc,
Hspa4l,
Plcd1,
Flna,
Rdx,
Serpina3k,
Stip1,
Ado,
Tnpo2,
Cfap36,
Spata20,
Psmd2,
Paip1,
Hsp90b1,
Trf,
Psmd3,
Uba1,
Usp5,
Vcl,
Fam49b,
Tkfc,
Ywhae,
Gsn,
Dlgap4,
Tardbp,
Txnrd3,
Ipo7,
Aars,
Tnpo1,
Cul3,
Vcp,
Efhd2,
Nsfl1c,
Nasp,
Ppp2r1a,
Tsnax,
Eef1b2,
Uso1,
Tpm3,
Actn4,
Vps35,
Xpo7,
Tbcb,
Spesp1,
Ift27,
Tomm34,
Ift172,
Slc44a2,
Rabl2,
Psmd11,
Wdr77,
Ipo5,
Sfpq,
Shcbp1l,
Dpep3,
Cand1,
Cul5,
Erp44,
Rrbp1,
Cul4a
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
20153004 |
Glycosylphosphatidylinositol-specific phospholipase D improves glucose tolerance. Metab. Clin. Exp. Nandita S Raikwar , Rosario F Bowen-Deeg , X Sean Du , Martin G Low , Mark A Deeg |
2010-10-01 | - |
17720976 |
J Biol Chem Kazuhide Watanabe , Caterina Bianco , Luigi Strizzi , Shin Hamada , Mario Mancino , Veronique Bailly , Wenjun Mo , Dingyi Wen , Konrad Miatkowski , Monica Gonzales , Michele Sanicola , Masaharu Seno , David S Salomon |
2007-10-26 | - |
17330941 |
Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides. J. Proteome Res. Oliver K Bernhard , Eugene A Kapp , Richard J Simpson |
2007-03-01 |
Pzp,
Lyve1,
Cfd,
Ahsg,
Apoh,
Serpinc1,
Azgp1,
Serping1,
C4b,
C4bp,
Serpina6,
Cfh,
Cfi,
Clu,
Col1a1,
Cp,
Egfr,
Ces1c,
F13b,
F2,
Fn1,
Gc,
Gpld1,
Cfb,
H2-Q10,
Hc,
Igh-VJ558,
Itih1,
Itih2,
Klkb1,
Kng1,
Lum,
Mug1,
Orm1,
Pon1,
Apcs,
Serpina1a,
Serpina3k,
Serpina10,
Trf,
Ttr,
Vtn,
Afm,
Ighg2a,
Ighg3,
C1ra,
Hgfac,
Fetub,
Proz,
Cpn2,
IGHA2
|
16822939 |
Am J Physiol Cell Physiol George M Verghese , Michael F Gutknecht , George H Caughey |
2006-12-01 | - |
16944957 |
Proteome-wide characterization of N-glycosylation events by diagonal chromatography. J. Proteome Res. Bart Ghesquière , Jozef Van Damme , Lennart Martens , Joël Vandekerckhove , Kris Gevaert |
2006-09-01 |
C8b,
Pzp,
Ace,
Cfd,
Ahsg,
Apoh,
Serpinc1,
Serping1,
C1qa,
C9,
Serpina6,
Cfh,
Cfi,
Clu,
Cp,
Csf1r,
Egfr,
Ces1c,
F10,
F13b,
Flt4,
Fn1,
Fstl1,
Gpld1,
Cfb,
Hc,
Serpind1,
Hp,
Ifnar2,
Il1r2,
Itih1,
Itih2,
Itih3,
Napsa,
Klkb1,
Kng1,
Lamp1,
Lcat,
Lum,
Masp2,
Mug1,
Mup3,
Orm1,
Orm2,
Pltp,
Proc,
Sirpa,
Nptn,
Serpina1b,
Serpina1c,
Serpina1e,
Serpina3k,
Serpina3m,
Serpina10,
Tnc,
Serpina3f,
Btd,
Ceacam1,
Afm,
Hgfac,
Cpb2,
Pglyrp2,
Pcyox1,
C8g,
Cpn2,
Mfap4
|
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