| Type | Description |
|---|---|
| Definition | APC down-regulated 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:17:00 | Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer. | 33673279 |
| 2019-08-24 11:51:00 | Through integrative analysis, we identify MEIS1 as a super-enhancer-driven oncogene, which co-operates with EWS-FLI1 in transcriptional regulation, and plays a key pro-survival role in Ewing sarcoma. Moreover, APCDD1, another super-enhancer-associated gene, acting as a downstream target of both MEIS1 and EWS-FLI1, is also characterized as a novel tumor-promoting factor in this malignancy | 30496486 |
| 2017-08-26 11:56:00 | Thus, we have provided the first evidence that APCDD1 expression is epigenetically silenced in OS, which may facilitate invasion and metastasis of OS cells. | 28698141 |
| 2017-04-29 10:57:00 | these novel findings suggest that APCDD1 positively regulates adipogenic differentiation and that its down-regulation by miR-130 during diet-induced obesity may contribute to impaired adipogenic differentiation and obesity-related metabolic disease. | 28242765 |
| 2016-05-07 11:20:00 | This study demonstrated a critical role for Apcdd1 in OL differentiation after white matter injury that points to a potential therapeutic approach for inhibiting Wnt signaling in these disorders. | 25946682 |
| Type | IDs |
|---|---|
| Synonymous | B7323, DRAPC1, FP7019, HHS, HTS, HYPT1 |
| Gene |
UniProtKB-ID:
APCD1_HUMAN
UniprotKB:
Q8J025
UniParc:
UPI000000D766
EMBL:
BC053324,
AF461902,
AK303076,
AB056722,
AB104887,
AK300743
Ensembl:
ENSG00000154856
KO:
hsa:147495
|
| Nucleutide sequences |
EMBL-CDS:
BAG62412.1,
BAC15563.1,
BAC65165.1,
AAH53324.1,
AAQ04816.1,
BAG64192.1
Gene_ORFName:
FP7019
Ensembl_TRS:
ENST00000355285
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347433
RefSeq:
NP_694545.1,
XP_011523905.1
|
| Others |
UniRef100:
UniRef100_Q8J025
UniRef90:
UniRef90_Q8J025
UniRef50:
UniRef50_Q8J025
UniGene:
Hs.293274
CCDS:
CCDS11849.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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