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14734 Gpc3

14734

Gpc3

glypican 3

protein-coding

Mus musculus

基因描述

Type Description
Definition glypican 3

研究结论

Date Results Publications
2019-10-12 13:00:00 This study provides first evidence for the inhibitory activity of Long non-coding RNA FENDRR in hepatocellular carcinoma, which is causally linked to targeting GPC3 at the epigenetic level. 30573358
2019-06-15 10:56:00 GPC3 might be an alternative therapeutic target for Hepatocellular carcinoma treatment based on a mouse study where Curcumin suppressed HCC tumor growth through down-regulating GPC3/wnt/beta-catenin signaling pathway. 30001951
2018-04-28 10:10:00 This study provides new insights into the roles of GPC1 and GPC3 in mandibular morphogenesis. GPC3-knockout reduces mandibular growth, but GPC1 does not. These findings along with previous studies indicate that glypicans could be potential therapeutic agents to manage craniosynostosis and associated bony dysmorphology. 28426184
2016-10-01 11:18:00 Data show that notum and glypican-1 and glypican-3 gene expression during colorectal cancer (CRC) development and present evidence to suggest them as potential new biomarkers of CRC pathogenesis. 26517809
2016-04-30 11:57:00 Coupling of pGPC3 to liposomes was essential for effective priming of GPC3-specific CTLs. 26616051

名称对应

Type IDs
Synonymous OCI-5
Gene
UniProtKB-ID: GPC3_MOUSE, Q3TWB2_MOUSE
UniprotKB: Q8CFZ4, Q3TWB2
UniParc: UPI00000236AF
EMBL: AK146702, AK168402, AK159764, BC036126
Ensembl: ENSMUSG00000055653
KO: mmu:14734
Nucleutide sequences
EMBL-CDS: AAH36126.1, BAE27369.1, BAE35354.1, BAE40323.1
Ensembl_TRS: ENSMUST00000069360
Protein sequencees
Ensembl_PRO: ENSMUSP00000064131
RefSeq: NP_057906.2
Others
UniRef100: UniRef100_Q8CFZ4
UniRef90: UniRef90_P51654-3
UniRef50: UniRef50_P51654-3
UniGene: Mm.22515
CCDS: CCDS30125.1

全选

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研究热度

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