| Type | Description |
|---|---|
| Definition | low density lipoprotein receptor-related protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:28:00 | Megalin-mediated albumin endocytosis in cultured murine mesangial cells. | 32736701 |
| 2020-12-26 13:15:00 | Sodium-glucose cotransporter 2 inhibition attenuates protein overload in renal proximal tubule via suppression of megalin O-GlcNacylation in progressive diabetic nephropathy. | 33069809 |
| 2020-12-19 13:44:00 | Beyond the tubule: pathological variants of LRP2, encoding the megalin receptor, result in glomerular loss and early progressive chronic kidney disease. | 33103447 |
| 2020-11-21 13:30:00 | Endothelial-specific deficiency of megalin in the brain protects mice against high-fat diet challenge. | 31937343 |
| 2020-07-18 12:04:00 | In proximal kidney tubules megalin binding to albumin is of lower affinity, and its expression is also essential for enabling the recovery of high concentrations of albumin in the fluid phase. | 32200668 |
| Type | IDs |
|---|---|
| Synonymous | AI315343, AW536255, D230004K18Rik, Gp330, Megalin, b2b1625.2Clo |
| Gene |
UniProtKB-ID:
LRP2_MOUSE
UniprotKB:
A2ARV4
UniParc:
UPI0000609058
EMBL:
Y08566,
AF197160,
AK166702,
AL845489
Ensembl:
ENSMUSG00000027070
KO:
mmu:14725
|
| Nucleutide sequences |
EMBL-CDS:
CAA69877.1,
BAE38957.1,
AAF61488.1
Ensembl_TRS:
ENSMUST00000080953
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000079752
RefSeq:
NP_001074557.1
|
| Others |
UniRef100:
UniRef100_A2ARV4
UniRef90:
UniRef90_A2ARV4
UniRef50:
UniRef50_A2ARV4
UniGene:
Mm.23847
CCDS:
CCDS38135.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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