| Type | Description |
|---|---|
| Definition | transmembrane channel like 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:18:00 | Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components. | 32917726 |
| 2019-09-07 10:14:00 | these findings suggest that the disruption of CIB1-EVER1-EVER2-dependent keratinocyte-intrinsic immunity underlies the selective susceptibility to beta-HPVs of epidermodysplasia verruciformis patients. | 30068544 |
| 2018-06-23 10:58:00 | The relatively high proportion of EV patients without mutation in TMC6/8 indicates the existence of EV-causing mutations in additional, presently unknown gene(s). However, a homozygous TMC8 splice site mutation in our patients resulted in aberrant transcripts which cannot retain the healthy phenotype | 28646613 |
| 2017-09-30 11:54:00 | The present study did not show any significant association of the EVER1/2 polymorphisms (rs2290907and rs16970849) with cervical cancer. | 27899077 |
| 2017-02-18 10:26:00 | There were no differences in Ever2 SNPs between head and neck squamous cell carcinoma patients with human papilloma virus (HPV)-positive and HPV-negative tumors, and healthy controls. | 27097911 |
| Type | IDs |
|---|---|
| Synonymous | EV2, EVER2, EVIN2 |
| Gene |
UniProtKB-ID:
TMC8_HUMAN,
B3KXZ8_HUMAN,
A0A024R8N8_HUMAN
UniprotKB:
Q8IU68,
B3KXZ8,
A0A024R8N8
UniParc:
UPI00004A294E,
UPI00000747D3,
UPI0000074471
EMBL:
CH471099,
AC021593,
AK090478,
BC110296,
BC028076,
AY057380,
AY099359,
AY236500,
AY099358,
AK128327
Ensembl:
ENSG00000167895
KO:
hsa:147138
|
| Nucleutide sequences |
EMBL-CDS:
AAL25837.1,
AAI10297.1,
BAC03459.1,
AAP69878.1,
AAM44454.1,
AAM44455.1,
BAG54660.1,
EAW89497.1,
EAW89494.1
Gene_ORFName:
hCG_2033776
Ensembl_TRS:
ENST00000318430,
ENST00000589691
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000325561,
ENSP00000467482
RefSeq:
XP_016879733.1,
XP_024306388.1,
XP_024306389.1,
XP_024306390.1,
XP_024306385.1,
XP_016879732.1,
XP_024306392.1,
XP_024306395.1,
NP_689681.2,
XP_024306393.1,
XP_016879731.1,
XP_024306391.1,
XP_024306386.1,
XP_024306394.1,
XP_024306387.1
|
| Others |
UniRef100:
UniRef100_B3KXZ8,
UniRef100_Q8IU68
UniRef90:
UniRef90_A0A0D9QYR8,
UniRef90_Q8IU68
UniRef50:
UniRef50_Q8IU68
UniGene:
Hs.592102
CCDS:
CCDS32749.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员