例如:"NBL1", "4681", "drought"
收藏
146956 EME1

146956

EME1

essential meiotic structure-specific endonuclease 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition essential meiotic structure-specific endonuclease 1

研究结论

Date Results Publications
2019-08-24 10:09:00 EME1 is regulated by CK2 in mitosis and after replication stress. 29850896
2018-04-28 11:18:00 The data suggest that subnuclear relocalization is relevant for the function of Mus81-Mms4 complex in response to DNA damage and, probably, of the endonucleases that colocalize with it. 28813668
2017-05-07 01:21:00 SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr). 27354282
2014-08-09 12:14:00 While Mus81-Eme1 shares several common features with members of the 5' flap nuclease family, the combined structural, biochemical, and biophysical analyses explain why Mus81-Eme1 preferentially cleaves 3' flap DNA substrates with 5' nicked ends. 24733841
2014-01-18 10:44:00 Data show that three structure-selective endonucleases, SLX1-SLX4, MUS81-EME1, and GEN1, define two pathways of Holliday junctions (HJs) resolution in HeLa cells. 24076221

名称对应

Type IDs
Synonymous MMS4L, SLX2A
Gene
UniProtKB-ID: EME1_HUMAN
UniprotKB: Q96AY2
UniParc: UPI000013DDDC, UPI00001AEAC6
EMBL: AK055926, BC016470
Ensembl: ENSG00000154920
KO: hsa:146956
Nucleutide sequences
EMBL-CDS: AAH16470.1, BAB71047.1
Ensembl_TRS: ENST00000393271, ENST00000511648, ENST00000338165
Protein sequencees
Ensembl_PRO: ENSP00000376952, ENSP00000339897, ENSP00000421700
RefSeq: NP_689676.2, XP_016879725.1, XP_011522697.1, XP_005257138.1, NP_001159603.1
Others
UniRef100: UniRef100_Q96AY2
UniRef90: UniRef90_Q96AY2
UniRef50: UniRef50_Q96AY2
UniGene: Hs.514330
CCDS: CCDS54141.1, CCDS11565.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员