| Type | Description |
|---|---|
| Definition | guanine nucleotide binding protein (G protein), beta 3 |
| Date | Results | Publications |
|---|---|---|
| 2015-05-16 11:24:00 | Ablation of the GNB3 gene in mice does not affect body weight, metabolism or blood pressure, but causes bradycardia. | 25093805 |
| 2013-12-14 12:02:00 | A transgenic model carries an extra copy of GNB3, weighs significantly more than wild-type littermates, and has excess fat accumulation. GNB3 is highly expressed in the brain, consistent with G-protein signaling involved in satiety and/or metabolism. | 23980137 |
| 2013-06-01 12:35:00 | These results suggest that the main role of Gbeta3 in cones is to establish optimal levels of transducin heteromer in the outer segment, thereby indirectly contributing to robust response properties. | 23516284 |
| 2012-11-03 11:10:00 | The results of this study showed that Gbeta(3) may play a role in synaptic maintenance since in its absence, the number of invaginating rod bipolar dendrites is greatly reduced, a deficit that was not observed at 3 weeks, the end of the developmental period. | 22895717 |
| 2010-01-21 00:00:00 | Gbeta3 subunit is coexpressed in physiologically ON-type cone bipolar cells with Ggamma13 and Gbeta4 but is not present in OFF-type bipolar cells. | 12454992 |
| Type | IDs |
|---|---|
| Synonymous | Gnb-3 |
| Gene |
UniProtKB-ID:
GBB3_MOUSE,
Q54AE3_MOUSE
UniprotKB:
Q61011,
Q54AE3
UniParc:
UPI0000001096
EMBL:
AK014789,
AB042402,
U38494,
AC002397,
BC018239
Ensembl:
ENSMUSG00000023439
KO:
mmu:14695
|
| Nucleutide sequences |
EMBL-CDS:
AAB01725.1,
AAC36013.1,
AAH18239.1,
BAB29553.1,
BAB17756.1
Ensembl_TRS:
ENSMUST00000024206
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024206
RefSeq:
NP_038558.1
|
| Others |
UniRef100:
UniRef100_Q61011
UniRef90:
UniRef90_P16520
UniRef50:
UniRef50_P16520
UniGene:
Mm.68889
CCDS:
CCDS20532.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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