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14687 Gnaz

14687

Gnaz

guanine nucleotide binding protein, alpha z subunit

protein-coding

Mus musculus

基因描述

Type Description
Definition guanine nucleotide binding protein, alpha z subunit

研究结论

Date Results Publications
2017-11-18 10:56:00 present study suggest that Gnaz links the circadian clockwork-via dopamine acting on D4 receptors-to G protein-mediated signaling in intact but not diabetic retina 29088301
2017-09-09 10:26:00 Galphaz plays a key role in beta-cell signaling that becomes dysfunctional in the type 1 diabetes setting, accelerating the death of beta-cells, which promotes further accumulation of immune cells in the pancreatic islets, and inhibiting a restorative proliferative response. 28419211
2012-09-22 10:37:00 Deletion of GalphaZ protein protects against diet-induced glucose intolerance via expansion of beta-cell mass. 22457354
2011-04-16 11:09:00 a novel role of Galpha(z) in restraining myogenic differentiation through the disruption of Rho signaling 20946953
2010-01-21 00:00:00 The active form of Galpha(z), but not Galpha(i2), is crucial for maintenance of the structure of the Golgi apparatus 12414994

名称对应

Type IDs
Synonymous AI847979, Gz
Gene
UniProtKB-ID: GNAZ_MOUSE, Q542R8_MOUSE
UniprotKB: O70443, Q542R8
UniParc: UPI0000004147
EMBL: AF056973, AF056972, AK133483, BC014702, L17074, AK080716
Ensembl: ENSMUSG00000040009
KO: mmu:14687
Nucleutide sequences
EMBL-CDS: AAC13568.1, AAC13569.1, AAH14702.1, AAC37651.1, BAE21680.1, BAC37989.1
Ensembl_TRS: ENSMUST00000037813, ENSMUST00000159991
Protein sequencees
Ensembl_PRO: ENSMUSP00000124639, ENSMUSP00000036087
RefSeq: NP_001345777.1, XP_006513299.1, XP_006513298.1, NP_034441.1
Others
UniRef100: UniRef100_O70443
UniRef90: UniRef90_P19086
UniRef50: UniRef50_P19086
UniGene: Mm.32595, Mm.393508
CCDS: CCDS23922.1

全选

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