| Type | Description |
|---|---|
| Definition | guanine nucleotide binding protein, alpha transducing 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-08-06 10:46:00 | Data suggest light reduces oxygen consumption rate (OCR) of retina; light does not affect OCR in retinas of Gnat1-/- knockout mice (phototransduction disabled). Light reduces cGMP in retina; light does not alter cGMP in Gnat1-/- plus Gnat2-/- retina. | 26677218 |
| 2013-08-03 11:31:00 | The Gnat2(c.518A>G) mouse contains a missense mutation that results in no cone function due to a misfolding of transducin. Cone photoreceptors also show signs of opsin mislocalization, retinal remodeling and degeneration. | 23580486 |
| 2010-01-21 00:00:00 | The Gnat2(cpfl3) mutation leads to cone dysfunction and the progressive loss of cone alpha-transducin immunolabeling. | 17065522 |
| 2010-01-21 00:00:00 | rod and cone transducin alpha-subunits are functionally interchangeable and their signaling properties do not contribute to the intrinsic light sensitivity differences between rods and cones | 19815523 |
| Type | IDs |
|---|---|
| Synonymous | AW490837, Gnat-2, Gt-2, Tcalpha |
| Gene |
UniProtKB-ID:
GNAT2_MOUSE,
A2AE33_MOUSE
UniprotKB:
P50149,
A2AE33
UniParc:
UPI0000000E85
EMBL:
BC016272,
BC131943,
BC131941,
L10666
Ensembl:
ENSMUSG00000009108
KO:
mmu:14686
|
| Nucleutide sequences |
EMBL-CDS:
AAH16272.1,
AAC37650.1,
AAI31944.1,
AAI31942.1
Ensembl_TRS:
ENSMUST00000058669
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000053818
RefSeq:
XP_036018795.1,
XP_030108291.1,
NP_032167.1,
XP_006501071.1
|
| Others |
UniRef100:
UniRef100_P50149
UniRef90:
UniRef90_P50149
UniRef50:
UniRef50_P50149
UniGene:
Mm.439652
CCDS:
CCDS17750.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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