| Type | Description |
|---|---|
| Definition | phosphoinositide-3-kinase regulatory subunit 6 |
| Date | Results | Publications |
|---|---|---|
| 2016-06-28 11:17:00 | Our findings suggest that p84 binding to p110gamma may represent a novel negative feedback signal that terminates PI3Kgamma activity. | 25753393 |
| 2014-01-04 12:16:00 | expression and activities of PI3Kgamma are modified differently by p87 and p101 in vitro and in living cells, arguing for specific regulatory roles of the non-catalytic subunits in the differentiation of PI3Kgamma signaling pathways. | 24014027 |
| 2012-11-03 14:21:00 | knockdown of p84 in MDA-MB-231 cells enhanced Akt phosphorylation and lung colonization | 21996737 |
| 2012-09-29 11:07:00 | GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4. | 22728827 |
| 2010-01-21 00:00:00 | ablation of PI3Kgamma reduced SDF1alpha-induced integrin activation in human EPCs and in murine Lin(-) BM-derived progenitor cells | 18323525 |
| Type | IDs |
|---|---|
| Synonymous | C17orf38, HsT41028, p84 PIKAP, p87(PIKAP), p87PIKAP |
| Gene |
UniProtKB-ID:
PI3R6_HUMAN,
B3KRK9_HUMAN
UniprotKB:
Q5UE93,
B3KRK9
UniParc:
UPI00003E28D0,
UPI0000043463
EMBL:
AC003695,
AL833037,
AK091819,
AC009451,
AY753192
Ensembl:
ENSG00000276231
KO:
hsa:146850
|
| Nucleutide sequences |
EMBL-CDS:
CAH56340.1,
AAV30085.1,
BAG52421.1
Ensembl_TRS:
ENST00000619866
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000480157
RefSeq:
XP_011521983.1,
XP_011521988.1,
XP_016879718.1,
XP_024306381.1,
XP_011521979.1,
NP_001010855.1,
XP_016879719.1,
XP_011521982.1,
XP_016879720.1,
XP_011521985.1,
XP_011521980.1,
XP_016879717.1,
NP_001277140.1
|
| Others |
UniRef100:
UniRef100_B3KRK9,
UniRef100_Q5UE93
UniRef90:
UniRef90_Q5UE93,
UniRef90_B3KRK9
UniRef50:
UniRef50_Q3U6Q4,
UniRef50_A0A452UTR2
UniGene:
Hs.255809
CCDS:
CCDS73985.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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