| Type | Description |
|---|---|
| Definition | guanine nucleotide binding protein, alpha transducing 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 11:27:00 | In conclusion, deletion of transducin1 (and the resulting inhibition of phototransduction in rod cells) inhibits the development of retinal vascular pathology in early diabetic retinopathy. | 30994864 |
| 2019-08-17 10:21:00 | we generated double-mutant (Pde6c(cpfl1/cpfl1)Gnat1(IRD2/IRD2)) mice with absent rod and cone photoreceptor function, and we evaluated their response for restoring rod (GNAT1) function through gene therapy | 30064895 |
| 2019-05-11 10:16:00 | an estimate for the electrical effect from a single transducin-cGMP-phosphodiesterase catalytic subunit molecular complex in intact mouse rods., is reported | 30796193 |
| 2018-05-19 10:39:00 | GNAT1 role in phototransduction of rod photoreceptors | 28320964 |
| 2016-08-06 11:49:00 | Data suggest light reduces oxygen consumption rate (OCR) of retina; light does not affect OCR in retinas of Gnat1-/- knockout mice (phototransduction disabled). Light reduces cGMP in retina; light does not alter cGMP in Gnat1-/- plus Gnat2-/- retina. | 26677218 |
| Type | IDs |
|---|---|
| Synonymous | Gnat-1, Ird1, Ird2, Tralpha, irdc, irdr, transducin |
| Gene |
UniProtKB-ID:
GNAT1_MOUSE
UniprotKB:
P20612
UniParc:
UPI0000001508
EMBL:
M25508,
U38504,
M25509,
M25506,
BC058810,
M25510,
M25512,
M25511,
BC022793,
BC051412,
M25513,
M25507
Ensembl:
ENSMUSG00000034837
KO:
mmu:14685
|
| Nucleutide sequences |
EMBL-CDS:
AAB01735.1,
AAA40473.1,
AAH22793.1,
AAH51412.2,
AAH58810.1
Ensembl_TRS:
ENSMUST00000010205
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000010205
RefSeq:
NP_032166.1
|
| Others |
UniRef100:
UniRef100_P20612
UniRef90:
UniRef90_P11488
UniRef50:
UniRef50_P11488
UniGene:
Mm.284853
CCDS:
CCDS23504.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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