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146760 RTN4RL1

146760

RTN4RL1

reticulon 4 receptor like 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition reticulon 4 receptor like 1

研究结论

Date Results Publications
2019-10-12 10:24:00 RTN4RL1 plays an important role in promoting the EMT of nasopharyngeal carcinoma (NPC) by regulating the phosphorylation of Src and FAK, thus activating their downstream pathways and eventually altering E-cadherin levels, F-actin polymerization, and cell polarity. Additionally, a high level of RTN4RL1 correlates with a poor prognosis of NPC. 29327067
2016-10-22 11:34:00 Duplication of 10q22.3-q23.3 encompassing NGR3 gene is associated with congenital heart disease, microcephaly, and mild intellectual disability 26383923
2012-03-17 12:24:00 Nogo receptor 3, a paralog of NgR1,functions as a NgR1 co-receptor for Nogo-66. 22133682
2010-01-21 00:00:00 predominantly expressed in the neurons of the embryonic and adult nervous systems 14664809

名称对应

Type IDs
Synonymous NGRH2, NgR3
Gene
UniProtKB-ID: R4RL1_HUMAN
UniprotKB: Q86UN2
UniParc: UPI000018CD23
EMBL: AF532859, BK001305, AL834409, CH471108, AY250219, BC128608
Ensembl: ENSG00000185924
KO: hsa:146760
Nucleutide sequences
EMBL-CDS: DAA01388.1, CAD39071.1, EAW90570.1, AAP21836.1, AAP82836.1, AAI28609.1
Ensembl_TRS: ENST00000331238
Protein sequencees
Ensembl_PRO: ENSP00000330631
RefSeq: NP_848663.1
Others
UniRef100: UniRef100_Q86UN2
UniRef90: UniRef90_Q86UN2
UniRef50: UniRef50_Q86UN2
UniGene: Hs.22917
CCDS: CCDS45569.1

全选

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研究热度

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