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146713 RBFOX3

146713

RBFOX3

RNA binding fox-1 homolog 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition RNA binding fox-1 homolog 3

研究结论

Date Results Publications
2018-07-07 11:58:00 RBFOX3 knockdown synergized with 5-FU to inhibit the growth and invasion of HCC cells through PI3K/AKT and epithelial-mesenchymal transition (EMT) signaling, and promote apoptosis by activating the cytochrome-c/caspase signaling pathway. 29689552
2017-12-23 11:46:00 In human lung tissue, Claudin-1 is higher in RBFOX3-positive cells than in RBFOX3-negative cells. Immunostaining and mRNA quantification revealed that protein levels, but not mRNA levels, of Claudin-1 are increased by RBFOX3. 28126724
2017-06-24 10:41:00 SNPs (rs9900428, rs9907432 and rs7211029) in RBFOX3 associate with sleep latency. 27142678
2017-04-08 10:58:00 this study show that TGF-beta-induced RBFOX3 inhibition plays an important role in epithelial-mesenchymal transition and lung cancer progression 27432190
2017-03-04 12:46:00 NeuN was recently eventually identified as an epitope of Rbfox3. NeuN is highly conserved among species and is stably expressed during specific stages of development. NeuN has been considered to be a reliable marker of mature neurons, however, this role has been challenged by recent studies indicating that NeuN staining is variable and even absent during certain diseases and states. Review. 25680637

名称对应

Type IDs
Synonymous FOX-3, FOX3, HRNBP3, NEUN
Gene
UniProtKB-ID: RFOX3_HUMAN
UniprotKB: A6NFN3
UniParc: UPI000020041C, UPI00017A6FDB
EMBL: AC055858, AC142247, AC020689, AC021534, AC027824, AK293617, AC073624, AK293905
Ensembl: ENSG00000167281
KO: hsa:146713
Nucleutide sequences
EMBL-CDS: BAG57077.1, BAG57290.1
Ensembl_TRS: ENST00000584778, ENST00000580155
Protein sequencees
Ensembl_PRO: ENSP00000463653, ENSP00000462007
RefSeq: XP_024306361.1, NP_001337382.1, NP_001372776.1, NP_001372768.1, NP_001372747.1, NP_001372760.1, NP_001372774.1, NP_001372753.1, XP_016879700.1, NP_001372737.1, NP_001372771.1, NP_001372751.1, NP_001337380.1, NP_001372744.1, NP_001076044.1, NP_001372750.1, NP_001372775.1, NP_001372743.1, NP_001372741.1, NP_001372748.1, NP_001372740.1, NP_001372757.1, NP_001372773.1, XP_016879698.1, NP_001372735.1, NP_001372766.1, NP_001372758.1, XP_024306363.1, XP_011522669.1, NP_001372745.1, NP_001372754.1, NP_001372764.1, NP_001372742.1, NP_001372749.1, XP_016879697.1, NP_001372746.1, NP_001372739.1, XP_011522662.1, XP_011522668.1, NP_001372767.1, NP_001372763.1, XP_024306360.1, NP_001372738.1, XP_024306364.1, NP_001372734.1, NP_001372755.1, NP_001372756.1, NP_001372752.1, NP_001372733.1, NP_001372759.1, NP_001372772.1, NP_001372765.1, NP_001372769.1, NP_001372762.1, NP_001372770.1, NP_001372736.1, NP_001372761.1
Others
UniRef100: UniRef100_A6NFN3
UniRef90: UniRef90_A6NFN3
UniRef50: UniRef50_A6NFN3
UniGene: Hs.135229
CCDS: CCDS45805.1

全选

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研究热度

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