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1466 CSRP2

1466

CSRP2

cysteine and glycine rich protein 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition cysteine and glycine rich protein 2

研究结论

Date Results Publications
2019-11-02 11:43:00 Study showed that CSRP2, an invadopodial actin bundling protein, is upregulated by hypoxia in various breast cancer cell lines, as well as in pre-clinical and clinical breast tumor specimens and functionally characterized two hypoxia responsive elements within the proximal promoter of CSRP2 gene which are targeted by hypoxia-inducible factor-1 (HIF-1) and required for promoter transactivation in response to hypoxia. 29976963
2018-03-31 11:17:00 CSRP2 promoted cell proliferation, cell-cycle progression, in vitro colony formation and cell migration ability. Abnormal CSRP2 expression was associated with resistance to chemotherapy; sensitivity was restored by down-regulating CSRP2 expression. 28415593
2010-01-21 00:00:00 the effect of proteasome inhibition on IL-10 activation of the IL-10E1 pathway [Il-10E1] 12861049

名称对应

Type IDs
Synonymous CRP2, LMO5, SmLIM
Gene
UniProtKB-ID: CSRP2_HUMAN, A0A024RBB5_HUMAN
UniprotKB: Q16527, A0A024RBB5
UniParc: UPI000014104B
EMBL: U46006, U57646, BT019913, CH471054, BC000992, U95018, GQ891415
Ensembl: ENSG00000175183
KO: hsa:1466
Nucleutide sequences
EMBL-CDS: AAH00992.1, AAC51753.1, AAC51755.1, AAC27344.1, AAV38716.1, ADO22277.1, EAW97336.1, EAW97337.1
Gene_ORFName: hCG_27233
Ensembl_TRS: ENST00000546966, ENST00000311083
Protein sequencees
Ensembl_PRO: ENSP00000310901, ENSP00000450056
RefSeq: NP_001287894.1, NP_001312.1
Others
UniRef100: UniRef100_Q16527
UniRef90: UniRef90_Q16527
UniRef50: UniRef50_Q16527
UniGene: Hs.530904
CCDS: CCDS9015.1

全选

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研究热度

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