| Type | Description |
|---|---|
| Definition | F-box and leucine rich repeat protein 16 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | The F-box protein FBXL16 up-regulates the stability of C-MYC oncoprotein by antagonizing the activity of the F-box protein FBW7. | 32345600 |
| 2010-03-08 12:33:00 | the expression of FBXL16 reproducibly upregulated in p16INK4A and p14ARF knockdown HeLa cells | 20043084 |
| Type | IDs |
|---|---|
| Synonymous | C16orf22, Fbl16, c380A1.1 |
| Gene |
UniProtKB-ID:
FXL16_HUMAN
UniprotKB:
Q8N461
UniParc:
UPI0000141371,
UPI00003E283C
EMBL:
BC036680,
CH471112,
AE006464,
Z97653,
AK091054,
Z92544
Ensembl:
ENSG00000127585
KO:
hsa:146330
|
| Nucleutide sequences |
EMBL-CDS:
EAW85750.1,
BAG52271.1,
EAW85749.1,
AAH36680.1,
AAK61245.1
Ensembl_TRS:
ENST00000324361,
ENST00000562563,
ENST00000397621
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000318674,
ENSP00000455217,
ENSP00000380746
RefSeq:
XP_024305928.1,
NP_699181.2
|
| Others |
UniRef100:
UniRef100_Q8N461
UniRef90:
UniRef90_Q8N461
UniRef50:
UniRef50_Q8N461
UniGene:
Hs.513244
CCDS:
CCDS10421.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32345600 |
J Biol Chem Marion Morel , Krushangi N Shah , Weiwen Long |
2020-06-05 | - |
| 29499133 |
Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression. Mol. Cell Xing Liu , Justin M Reitsma , Jennifer L Mamrosh , Yaru Zhang , Ronny Straube , Raymond J Deshaies |
2018-03-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27880917 |
Cell Rep Nicole St-Denis , Gagan D Gupta , Zhen Yuan Lin , Beatriz Gonzalez-Badillo , Amanda O Veri , James D R Knight , Dushyandi Rajendran , Amber L Couzens , Ko W Currie , Johnny M Tkach , Sally W T Cheung , Laurence Pelletier , Anne-Claude Gingras |
2016-11-22 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 24255178 |
Sci Signal Amber L Couzens , James D R Knight , Michelle J Kean , Guoci Teo , Alexander Weiss , Wade H Dunham , Zhen-Yuan Lin , Richard D Bagshaw , Frank Sicheri , Tony Pawson , Jeffrey L Wrana , Hyungwon Choi , Anne-Claude Gingras |
2013-11-19 |
HDAC6,
HDAC5,
AKAP9,
MPHOSPH9,
PATJ,
DCAF7,
DENND4A,
PAK4,
BASP1,
YAP1,
TAB1,
BAIAP2,
PIBF1,
PFDN6,
SORBS1,
IGF2BP2,
PNMA2,
NUDC,
MAP3K2,
KIF1C,
NCKAP1,
SDCCAG3,
TUBGCP2,
RUVBL2,
SUGT1,
YWHAQ,
ILVBL,
KIF2C,
RAB35,
CDC42EP1,
GLMN,
ERLIN2,
RASSF1,
RASSF8,
SNX18,
NACC1,
WDR92,
CNTROB,
AGAP3,
SSX2IP,
AMER1,
DOCK11,
MPP7,
PLEKHA7,
MIPOL1,
CSNK1E,
FBXL16,
CTNNB1,
SPICE1,
CYLD,
RUNDC3B,
AMOT,
AMOTL1,
USP54,
AP2A1,
AP2A2,
AP1B1,
DBN1,
CCDC138,
DDX6,
ECH1,
PGAM5,
EIF4EBP1,
CRTC2,
MARK2,
DMTN,
EPS8,
ACSL3,
LNX2,
FAM83B,
ALDH3A2,
CEP162,
RAB11FIP2,
ANKRD26,
R3HDM2,
PPP6R1,
INPP5F,
RUFY3,
TRIM32,
NINL,
CEP131,
CEP152,
STK38L,
CNOT1,
SAMD4A,
UHRF1BP1L,
ERC1,
FOXO3,
SIPA1L3,
KIF1B,
TNRC6B,
CLASP2,
EPB41L3,
MAST2,
LRCH1,
FAM175B,
TBC1D1,
ANKRD28,
MTCL1
|
| 24035498 |
Mol. Cell Meng-Kwang Marcus Tan , Hui-Jun Lim , Eric J Bennett , Yang Shi , J Wade Harper |
2013-10-10 |
ZBTB18,
CLGN,
CETN2,
AHCYL1,
FBXL14,
FBXL16,
ACSF3,
FBXL13,
FBXL7,
DICER1,
PRAME,
FBXL2,
FBXL5,
FBXL4,
ERLEC1,
NFE2L2,
HPCAL4,
FAM96B,
SUFU,
WDR44,
FBXL19,
FBXL12,
EPS15P1,
BACH1,
WDR48,
RABGGTB,
MMS19,
FBXL17,
SKP1,
ZBTB10,
STYX,
FBXL18,
MUS81,
CUL1,
STRADA,
ZRANB2
|
| 21900206 |
A directed protein interaction network for investigating intracellular signal transduction. Sci Signal Arunachalam Vinayagam , Ulrich Stelzl , Raphaele Foulle , Stephanie Plassmann , Martina Zenkner , Jan Timm , Heike E Assmus , Miguel A Andrade-Navarro , Erich E Wanker |
2011-09-06 |
KCNE3,
HDAC6,
PDCD6IP,
ZNF605,
TOM1L1,
HMGXB4,
RANBP9,
RWDD2B,
SNUPN,
TSSC4,
ARPC3,
ACTR1B,
CDH13,
CEBPZ,
RBM5,
CDK4,
CDK5,
TRIM13,
EIF1,
DDX39A,
HNRNPR,
RABEPK,
SPRY2,
CDKN1A,
CDK2AP2,
LOC400927-CSNK1E,
RGS19,
CDKN2B,
DSCR3,
IKZF1,
NPM3,
TUBA1B,
TUBB3,
RACK1,
PIAS3,
NDC80,
YAP1,
CDIPT,
TUBGCP3,
TIMM17A,
TAB1,
FST,
STK25,
DEAF1,
KAT5,
GLRX3,
DCTN2,
PRDX4,
RABAC1,
DPYSL4,
CCT7,
CCT4,
DRAP1,
CENPB,
TXNIP,
NPRL2,
GNB5,
CERS1,
CFL1,
MGEA5,
PLK4,
RAI1,
GIPC1,
ZNF266,
UTP14A,
PGRMC1,
RAB10,
YIF1A,
JTB,
GADD45G,
AFG3L2,
C11orf58,
HNRNPA0,
PNRC1,
ADIRF,
COPS6,
IMMT,
SF3B2,
KIF2C,
RAB31,
ADAP1,
PIM2,
RCC1,
NUDT21,
SNRNP35,
CHD3,
STMN2,
HSF2BP,
SPACA9,
RPP14,
FGFR1OP,
FAF1,
ZWINT,
CHGA,
CDC37,
CHGB,
KAT7,
C14orf1,
NUDT5
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20043084 |
Int. J. Oncol. Kazuyuki Sato , Yusuke Kusama , Moe Tategu , Kenichi Yoshida |
2010-02-01 |
FBXL16
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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