| Type | Description |
|---|---|
| Definition | gap junction protein, alpha 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 11:50:00 | The Cx50-R205G mutation inhibits both central and equatorial lens epithelial cell proliferation to cause small lenses. | 32182330 |
| 2020-06-20 12:32:00 | CHOP is not the critical etiological factor for the cataracts observed in homozygous Cx50D47A lenses, further supporting a major role for connexins in the disease. | 31908399 |
| 2019-06-08 12:30:00 | Results show that electrostatic properties of the connexin-50 (Cx50) gap junction (GJ) pore are important for the channel conductance (gammaj) and the intracellular magnesium ([Mg(2+)]i) modulation. | 30287491 |
| 2017-05-13 11:55:00 | These results suggest that expression of Cx50D47A induces ER stress, triggering activation of the PERK-ATF4 pathway, which potentially contributes to the lens pathology and leads to increased expression of anti-apoptotic factors, allowing cell survival. | 27317663 |
| 2016-06-28 12:15:00 | Study showed that mouse horizontal cells establish a coupled dendritic network by Cx57 and two coupled axon terminal networks, one made of Cx50 and the other made of Cx57 channels | 25823610 |
| Type | IDs |
|---|---|
| Synonymous | Aey5, Cnx50, Cx50, Lop10 |
| Gene |
UniProtKB-ID:
CXA8_MOUSE,
Q548M7_MOUSE
UniprotKB:
P28236,
Q548M7
UniParc:
UPI00000009BC
EMBL:
GU363513,
BC125569,
GU363514,
M91243,
GU363515,
LT990385,
BC120513,
AF304357,
AF321120
Ensembl:
ENSMUSG00000049908
KO:
mmu:14616
|
| Nucleutide sequences |
EMBL-CDS:
AAA37497.1,
AAG42241.1,
ADC38984.1,
ADC38986.1,
AAG59880.1,
AAI20514.1,
VZP20185.1,
AAI25570.1,
ADC38985.1
Ensembl_TRS:
ENSMUST00000062944
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000049532
RefSeq:
NP_032149.1
|
| Others |
UniRef100:
UniRef100_P28236
UniRef90:
UniRef90_Q8K4Q9
UniRef50:
UniRef50_P48165
UniGene:
Mm.258183,
Mm.455421
CCDS:
CCDS17651.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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