Gja5 - gap junction protein, alpha 5-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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14613 Gja5

基因描述

Type	Description
Definition	gap junction protein, alpha 5

研究结论

Date	Results	Publications
2021-02-06 13:58:00	Conjugated activation of myocardial-specific transcription of Gja5 by a pair of Nkx2-5-Shox2 co-responsive elements.	32687896
2020-10-24 13:58:00	Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor gamma co-activator deficient hearts modelling mitochondrial dysfunction.	31778152
2020-02-01 11:01:00	Thus, while gestation and gross development were conserved in Cx40(-/-)Panx1(-/-) mice, they exhibit cardiac hypertrophy, hypertension, and impaired endothelial-mediated vasodilation that phenocopies Cx40(-/-) mice.	30745457
2019-11-16 11:11:00	findings reveal a role of Cx40 in regulation of ROCK1 and MLC20 that contributes critically to lung vascular barrier failure in acute lung injury.	30234377
2019-08-31 11:40:00	Deletion of Cx40 decreases the calcium sensitivity of renin-secreting juxtaglomerular cells.	29427253

名称对应

Type	IDs
Synonymous	5730555N10Rik, Cnx40, Cx40, Gja-5
Gene	UniProtKB-ID: CXA5_MOUSE, A0A654ICB8_MOUSE UniprotKB: Q01231, A0A654ICB8 UniParc: UPI0000026528 EMBL: LT990381, X61675, BC053054 Ensembl: ENSMUSG00000057123 KO: mmu:14613
Nucleutide sequences	EMBL-CDS: AAH53054.1, CAA43850.1, VZP20181.1 Ensembl_TRS: ENSMUST00000072600
Protein sequencees	Ensembl_PRO: ENSMUSP00000088264 RefSeq: NP_001258557.1, NP_032147.1
Others	UniRef100: UniRef100_Q01231 UniRef90: UniRef90_Q01231 UniRef50: UniRef50_P36382 UniGene: Mm.281816 CCDS: CCDS17652.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
33082351	Nkx2-5 defines distinct scaffold and recruitment phases during formation of the murine cardiac Purkinje fiber network. Nat Commun Caroline Choquet , Robert G Kelly , Lucile Miquerol	2020-10-20	-
32883967	In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix. Nat Commun Jiyoung Lee , Akito Sutani , Rin Kaneko , Jun Takeuchi , Tetsuo Sasano , Takashi Kohda , Kensuke Ihara , Kentaro Takahashi , Masahiro Yamazoe , Tomohiro Morio , Tetsushi Furukawa , Fumitoshi Ishino	2020-09-03	-
32687896	Conjugated activation of myocardial-specific transcription of Gja5 by a pair of Nkx2-5-Shox2 co-responsive elements. Dev Biol Tianfang Yang , Zhen Huang , Hua Li , Linyan Wang , YiPing Chen	2020-09-01	-
32675240	T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system. Proc Natl Acad Sci U S A Rajiv A Mohan , Fernanda M Bosada , Jan H van Weerd , Karel van Duijvenboden , Jianan Wang , Mathilda T M Mommersteeg , Ingeborg B Hooijkaas , Vincent Wakker , Corrie de Gier-de Vries , Ruben Coronel , Gerard J J Boink , Jeroen Bakkers , Phil Barnett , Bas J Boukens , Vincent M Christoffels	2020-08-04	-
32672536	Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction. Elife Jan Hendrik van Weerd , Rajiv A Mohan , Karel van Duijvenboden , Ingeborg B Hooijkaas , Vincent Wakker , Bastiaan J Boukens , Phil Barnett , Vincent M Christoffels	2020-07-16	-
32383994	Reduced Na⁺ current in Purkinje fibers explains cardiac conduction defects and arrhythmias in Duchenne muscular dystrophy. Am J Physiol Heart Circ Physiol Janine Ebner , Pavel Uhrin , Petra L Szabo , Attila Kiss , Bruno K Podesser , Hannes Todt , Karlheinz Hilber , Xaver Koenig	2020-06-01	-
32251422	O-linked Î²-N-acetylglucosamine transferase plays an essential role in heart development through regulating angiopoietin-1. PLoS Genet Yongxin Mu , Houzhi Yu , Tongbin Wu , Jianlin Zhang , Sylvia M Evans , Ju Chen	2020-04-01	-
31306714	Gradual differentiation and confinement of the cardiac conduction system as indicated by marker gene expression. Biochim Biophys Acta Mol Cell Res Vincent W W van Eif , Sonia Stefanovic , Rajiv A Mohan , Vincent M Christoffels	2020-03-01	-
31778152	Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor Î³ co-activator deficient hearts modelling mitochondrial dysfunction. Biosci Rep Charlotte E Edling , Ibrahim T Fazmin , Khalil Saadeh , Karan R Chadda , Shiraz Ahmad , Haseeb Valli , Christopher L-H Huang , Kamalan Jeevaratnam	2019-12-20	-
31836710	Molecular determinants of nephron vascular specialization in the kidney. Nat Commun David M Barry , Elizabeth A McMillan , Balvir Kunar , Raphael Lis , Tuo Zhang , Tyler Lu , Edward Daniel , Masataka Yokoyama , Jesus M Gomez-Salinero , Angara Sureshbabu , Ondine Cleaver , Annarita Di Lorenzo , Mary E Choi , Jenny Xiang , David Redmond , Sina Y Rabbany , Thangamani Muthukumar , Shahin Rafii	2019-12-13	-

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